Results 191 to 200 of about 2,679,339 (286)
Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul +4 more
wiley +1 more source
Nutcracker syndrome: A novel endovascular anchoring technique for left renal vein stenting. [PDF]
Bayat I, Koo MPM, Goh D.
europepmc +1 more source
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
Left Renal Vein Transection and Reconstruction for Functional Paraganglioma Resection: A Case Report. [PDF]
Boo YJ, Han SU, Hur H, Bang JB.
europepmc +1 more source
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song +6 more
wiley +1 more source
Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang +9 more
wiley +1 more source
Unilateral anomalous lateral branch of the abdominal aorta piercing the left renal vein - A case report. [PDF]
Shetty SD +3 more
europepmc +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Using finite element analysis to obtain the pressure gradient between the left renal vein and the inferior vena cava: a new method for the diagnosis and follow-up of patients with nutcracker syndrome. [PDF]
Xu Z +15 more
europepmc +1 more source

