Results 61 to 70 of about 2,672,697 (288)

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Left Renal Vein Pseudo-Fenestration

Reports
We describe a rare case of LRV pseudo-fenestration in a 68-year-old female identified on contrast-enhanced multidetector computed tomography. Unlike true fenestration, in which a single vessel splits and reunites, this pseudo-fenestration resulted from ...
Daniel Gondorf, George Triantafyllou, Nikolaos-Achilleas Arkoudis, Georgios Velonakis, Kostis Gyftopoulos, Maria Piagkou   +5 more
doaj   +1 more source

Terminal bifurcation and unusual communication of left testicular vein with the left suprarenal vein

Jornal Vascular Brasileiro, 2017
Variations of the testicular veins are relevant in clinical cases of varicocele and in other therapeutic and diagnostic procedures. We report herein on a unique variation of the left testicular vein observed in an adult male cadaver.
Satheesha Badagabettu Nayak, Ashwini Aithal Padur, Naveen Kumar, Deepthinath Reghunathan   +3 more
doaj   +1 more source

Combined Nutcracker and Ehlers-Danlos Syndromes: A Case Report

EJVES Vascular Forum, 2020
Introduction: Nutcracker syndrome refers to the clinical manifestations of left renal vein compression between the superior mesenteric artery and the abdominal aorta, causing urinary changes and low back pain.
Alexandre Campos Moraes Amato, Arthur Ethan Cardoso da Silva, Isabela Moraes Bernal, Julia Cuginotti de Oliveira, Maísa Di Paschoal Almeida Ribeiro, Priscila Souza Schinzari, Ricardo Virgínio dos Santos   +6 more
doaj   +1 more source

Initial Division of the Left Renal Vein before Dissection of Left Renal Vein Occluded by Intracaval Tumor Thrombus [PDF]

, 2011
Between November 2008 and March 2010, we performed initial division of the left renal vein occluded by the tumor thrombus in six cases of left renal cancer at Toranomon Hospital.
安部, 光洋, 岡根谷, 利一, 小松, 秀樹, 藤岡, 正志, 元島, 崇信, 黒澤, 和宏, 森川, 弘史, 沖田, 竜治   +7 more
core  

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

INAPPROPRIATE LEFT VENTRICULAR MASS, IN CHILDREN WITH PREDYALITIC CHRONIC RENAL INSUFFICIENCY [PDF]

, 2008
Background: Increased left ventricular (LV) mass in children with chronic renal insufficiency (CRI) might represent an adaptive mechanism to compensate for increased workload.
Romano, Carmela
core   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Reimplantation of the left renal vein in case of nutcracker syndrome: a 25-year experience of one center

Zaporožskij Medicinskij Žurnal
The aim was to assess the long-term outcomes of the left renal vein reimplantation in case of nutcracker syndrome. Materials and methods. The study included 56 patients with critical stenosis of the left renal vein who underwent left renal vein ...
I.I. Kobza, I. R. Nesterenko
doaj   +1 more source