Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu +9 more
wiley +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
Identification of Anticoagulation Benefit Subgroups of Patients With Left Ventricular Thrombus
Background: Left ventricular thrombus (LVT) is associated with major adverse cardiovascular and cerebrovascular events (MACCEs). Anticoagulation represents the current primary management for LVT; however, current studies in some Asian ...
Zechen Liu +4 more
doaj +1 more source
Left ventricular hypertrophy [PDF]
Left ventricular hypertrophy is often assumed to be little more than a marker for hypertension. In fact, the relation between diastolic or systolic blood pressure and left ventricular mass is not always close.1 2 Left ventricular hypertrophy is an independent risk factor for myocardial infarction and death in men and women with hypertension3 4 and in ...
openaire +2 more sources
Prevalence and significance of alterations in cardiac structure and function in patients with heart failure and a preserved ejection fraction [PDF]
<p><b>Background:</b> The purpose of this study was to examine the prevalence of abnormalities in cardiac structure and function present in patients with heart failure and a preserved ejection fraction (HFPEF) and to determine whether ...
Michel Komajda +18 more
core +1 more source
Left ventricular end-diastolic pressure predicts in-hospital outcomes in takotsubo syndrome
Aims: Takotsubo syndrome (TTS) is associated to serious adverse in-hospital complications. We evaluated the role of invasively assessed left ventricular end-diastolic pressure (LVEDP) for predicting in-hospital complications in TTS patients compared to ...
Meucci MC +11 more
core +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Incessant left ventricular tachycardia of unusual etiology
Apart from Coronary artery disease, left ventricular tachycardia may result from cardiac sarcoidosis, left ventricular tumor, chagas disease and idiopathic left ventricular tachycardia.
Praloy Chakraborty +3 more
doaj +1 more source
PDE2 activity differs in right and left rat ventricular myocardium and differentially regulates β2 adrenoceptor-mediated effects [PDF]
The important regulator of cardiac function, cAMP, is hydrolyzed by different cyclic nucleotide phosphodiesterases (PDEs), whose expression and activity are not uniform throughout the heart. Of these enzymes, PDE2 shapes β1 adrenoceptor-dependent cardiac
Handschin, Christoph +11 more
core +1 more source

