Results 131 to 140 of about 115,017 (359)
Advanced Science, EarlyView.A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni +6 more
wiley +1 more source
Left Ventricular Assist Device-Associated Infections: Case Series
Journal of Global Antimicrobial ResistanceAIM: We evaluate the epidemiological, laboratory, and clinical data of left ventricular assist device (LVAD)-associated infections diagnosed based on clinical evaluation, imaging studies, and microbiologic tests.
Bahar Busra Sivrikaya, Ozgur Gunal
doaj +1 more source
A Case of HeartMate 3 Outflow Graft Twisting with Extraluminal Thrombosis: Is Computed Tomography Angiography Helpful? [PDF]
, 2020 Twists in the outflow graft of the HeartMateTM 3 device (Abbott) have recently been described as a sporadic, late complication. We present a case with a unique combination of external compression of the HeartMate 3 outflow graft by a surgical scar ...
Guglin, Maya +3 more
core +1 more source
FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine
Advanced Science, EarlyView.This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang +15 more
wiley +1 more source
Journal of Chest SurgeryBackground: Left ventricular assist devices (LVADs) are widely employed as a therapeutic option for end-stage heart failure. We evaluated the outcomes associated with centrifugal- flow LVAD implantation, comparing 2 device models: the Heartmate 3 (HM3)
Kinam Shin +6 more
doaj +1 more source
Advanced Science, EarlyView.This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun +12 more
wiley +1 more source
Thyrotoxicosis-facilitated bridge to recovery with a continuous-flow left ventricular assist device [PDF]
, 2017 The HeartMate II is a continuous-flow left ventricular assist device that can be explanted from patients after cardiac recovery. We implanted a HeartMate II in a 21-year-old man who had idiopathic cardiomyopathy. A year later, he developed thyrotoxicosis,
Frazier, O.H. +2 more
core
Cutting the Cord: A Case of Late Presenting Driveline Infection [PDF]
, 2020 Ventricular assist device (VAD) related infection, specifically driveline infection, is a common complication after VAD implantation. A 45-year old patient with a delayed skin infection at the site of the original driveline nearly one year after VAD ...
Eyadiel, Lauren +2 more
core +1 more source
Development and characterization of the arterial windkessel and its role during left ventricular assist device assistance [PDF]
, 2015 Modeling of the cardiovascular system is challenging, but it has the potential to further advance our understanding of normal and pathological conditions. Morphology and function are closely related. The arterial system provides steady blood flow to each
Capoccia, Massimo
core +1 more source
Circulation: Heart Failure, 2017 Background— Left ventricular assist device–supported patients are usually anticoagulated with a combination of aspirin and vitamin K antagonists. Long-term vitamin K antagonist therapy can be complicated by unstable international normalized ratio values ...
M. Andreas +11 more
semanticscholar +1 more source