Results 151 to 160 of about 111,089 (390)

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

open access: yesAdvanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang   +12 more
wiley   +1 more source

Passive control of a bi-ventricular assist device : an experimental and numerical investigation [PDF]

open access: yes, 2008
For the last two decades heart disease has been the highest single cause of death for the human population. With an alarming number of patients requiring heart transplant, and donations not able to satisfy the demand, treatment looks to mechanical ...
Gaddum, Nicholas Richard
core   +1 more source

Rotary mechanical circulatory support systems

open access: yes, 2017
A detailed survey of the current trends and recent advances in rotary mechanical circulatory support systems is presented in this paper. Rather than clinical reports, the focus is on technological aspects of these rehabilitating devices as a reference ...
Bonnell, Mark   +3 more
core   +1 more source

Improved Results for Postcardiotomy Cardiogenic Shock With the Use of Implantable Left Ventricular Assist Devices [PDF]

open access: bronze, 1997
Joseph J. DeRose   +7 more
openalex   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

open access: yesAdvanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng   +9 more
wiley   +1 more source

Left ventricular assist device [PDF]

open access: yesCardiologia Croatica, 2016
Marija Čulo, Marija Renić
openaire   +1 more source

Depth‐Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain

open access: yesAdvanced Electronic Materials, EarlyView.
In this study, a depth‐adjustable, flexible 3D multi‐shank electrode array that produces precise neural recordings at various brain depths is developed. Integrating 2D flexible electrode arrays with a modular supporting board allowed the insertion depth to be easily adjusted without re‐fabrication.
Minseok Kim   +5 more
wiley   +1 more source

Early Expression of Pro- and Anti-Inflammatory Cytokines in Left Ventricular Assist Device Recipients With Multiple Organ Failure Syndrome [PDF]

open access: yes
To assess whether the combined evaluation of total Sequential Organ Failure Assessment (t-SOFA) score and pro- and anti-inflammatory cytokine profiles early after left ventricular assist device (LVAD) implant discriminates patients at high risk for ...
Caruso, Raffaele
core   +3 more sources

Critical Care Transthoracic Echocardiography

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2014
A 70-year-old man with end-stage heart failure and a continuous-flow left ventricular assist device received repeated electrical discharges from his biventricular implantable cardiac defibrillator.
Peter Mark Schulman MD   +5 more
doaj   +1 more source

Activation of coagulation and fibrinolytic pathways in patients with left ventricular assist devices [PDF]

open access: hybrid, 1996
Talia B. Spanier   +7 more
openalex   +1 more source

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