Results 191 to 200 of about 3,982,833 (247)
Artificial Organs, EarlyView.Preventable geometric failure modes, such as outflow graft kinking and inflow malposition, frequently cause HeartMate 3 dysfunction. This study identifies these complications as key drivers of device‐related morbidity, highlighting the importance of optimized surgical positioning to ensure long‐term device performance and improved clinical outcomes ...
Ali Saad Merzah +17 more
wiley +1 more source
Monitoring Mitochondrial Function With High‐Resolution Respirometry During Ex‐Situ Heart Perfusion
Artificial Organs, EarlyView.Normothermic ESHP preserves mitochondrial respiratory function over 6 h in a porcine model (n = 6): OXPHOS capacities across NADH‐, fatty‐acid‐, and succinate‐linked pathways remain stable, with reduced cytochrome‐c control efficiency indicating improved outer‐membrane integrity. HRR provides a rapid, actionable readout for organ assessment.
Lukas Stastny +12 more
wiley +1 more source
Artificial Organs, EarlyView.Integrating silver‐plated wound dressings into DLES care presents a safe and effective strategy for DLI prevention. Key findings include a 100% infection‐free rate in the Silverlon group, no NPWT and hospital readmission in the Silverlon group, and no severe DESTINE stages (3, 4) in the Silverlon group.
Barbara Veiter +9 more
wiley +1 more source
SURGELLA: A Scoping Review of Impella‐Assisted Hemodynamic Support in High‐Risk Non‐Cardiac Surgery
Artificial Organs, EarlyView.In selected patients with severe LV dysfunction, Impella‐supported non‐cardiac surgery may provide a temporary hemodynamic bridge to otherwise prohibitive procedures. Published evidence remains limited to a small number of highly selected cases, supporting technical feasibility rather than comparative benefit or generalizable safety.
Hussein Elghazaly +6 more
wiley +1 more source
Experimental Extracorporeal Circulation System: A Pilot Study in Rats
Artificial Organs, EarlyView.A miniature extracorporeal circulation (ECC) system was developed for reproducible rodent studies. This system incorporates an integrated heat exchanger and a silicone membrane oxygenator within a double‐lumen circuit, resulting in an ultralow priming volume of < 1.5 mL.
Akira T. Kawaguchi +7 more
wiley +1 more source
Progress Toward a Portable Artificial Lung: A Systematic Review
Artificial Organs, EarlyView.Eight portable respiratory assist devices were identified. The CE‐marked MobyBox and the FDA‐approved Breethe OXY‐1 system are in clinical use. Each device is substantially minimized to allow ambulation, but further work is required to address challenges related to anticoagulant management and safe mobilization. Created in BioRender. Svendsen, A. (2026)
Maja Munk Svendsen +5 more
wiley +1 more source
Artificial Organs, EarlyView.Quantitative assessment of a newly proposed CFD‐based biophysical model for predicting device‐induced platelet damage by circulatory assist devices was performed. The new model preserved the relative trends observed previously with the power‐law formulation across a range of clinically relevant pump operating conditions, while demonstrating improved ...
Anik Tarafder +3 more
wiley +1 more source
Artificial Organs, EarlyView.DESTINE 2.0 decision flowchart: stage‐based assessment and management of driveline exit‐site disorders. The flowchart provides a simplified decision‐support tool for the stage‐based evaluation and management of driveline exit‐site disorders in LVAD patients, intended as a practical complement to the staging pyramid (Figre 2) and the detailed staging ...
Alexander M. Bernhardt +7 more
wiley +1 more source
Artificial Organs, EarlyView.Here we investigated the development of a geometrically tunable blood for patients with single ventricle physiology. Two multiscale cardiovascular models were customized and implemented at timepoints spanning across the beginning and end of the shunt‐use period.
Ellen E. Garven +4 more
wiley +1 more source
Artificial Organs, EarlyView.Among selected patients receiving temporary right ventricular support, pooled survival to discharge was 60.4%, and separately pooled successful weaning was 60.6%. These descriptive estimates from 106 heterogeneous observational studies, predominantly involving concurrent left‐sided or biventricular support, cannot establish treatment benefit or ...
Hussein Elghazaly +5 more
wiley +1 more source