Results 81 to 90 of about 901,378 (420)

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu, Ziwei Pang, Jing Zhao, Jingyi Xue, Hsuan Lo, Tiancheng Gu, Ping Zhang, Jiawei Tian, Guo‐Qing Du   +8 more
wiley   +1 more source

Prognostic value of global longitudinal strain in hypertrophic cardiomyopathy: A systematic review and meta‐analysis

Clinical Cardiology, Volume 45, Issue 12, Page 1184-1191, December 2022., 2022
Abstract Background As previously reported, impairment of left ventricular global longitudinal strain (LVGLS) is associated with myocardial fibrosis, arrhythmias, and heart failure in hypertrophic cardiomyopathy (HCM) patients. Hypothesis This study aimed to estimate the association between LVGLS measured by echocardiography and major adverse ...
Ying Yang, Dong Wu, Hui Wang, Yanting Wang   +3 more
wiley   +1 more source

Impact of overweight on left ventricular function in type 2 diabetes mellitus

Cardiovascular Diabetology, 2017
Background Coexistence of left ventricular (LV) longitudinal myocardial systolic dysfunction with LV diastolic dysfunction could lead to heart failure with preserved ejection fraction (HFpEF).
Makiko Suto, Hidekazu Tanaka, Yasuhide Mochizuki, Jun Mukai, Hiroki Takada, Fumitaka Soga, Kumiko Dokuni, Yutaka Hatani, Keiko Hatazawa, Hiroki Matsuzoe, Hiroyuki Sano, Hiroyuki Shimoura, Junichi Ooka, Kensuke Matsumoto, Yushi Hirota, Wataru Ogawa, Ken-ichi Hirata   +16 more
doaj   +1 more source

Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction

Advanced Materials, EarlyView.
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang, Zilu Xu, Feiyang Zheng, Dongcheng Yang, Kaige Xu, Ming Ke, Xiao Zhou, Xiaohan Zhang, Ju Tan, Yong Liu, Yansha Hao, Malcolm Xing, Chuhong Zhu   +12 more
wiley   +1 more source

Diastolic cardiac function in connective tissue dysplasia

Лечащий Врач, 2021
The article analyzes literature data on the diagnostics of diastolic function condition in young patients with signs of connective tissue dysplasia. The problem of diagnostics of pre-clinical left-ventricular diastolic dysfunction was discussed, as well ...
Yu. V. Tereschenko, G. I. Nechaeva, V. V. Potapov, M. I. Shupina, E. N. Loginova, E. V. Nadey, T. P. Kabanenko   +6 more
doaj  

Left atrial size in patients with arterial hypertension [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2006
INTRODUCTION Left atrial size is increased in patients with arterial hypertension. Left atrial enlargement represents a risk factor of atrial fibrillation and stroke. Left atrial size depends on the effect of many other etiological factors, predominantly
Milutinović Suzana, Apostolović Svetlana, Tasić Ivan   +2 more
doaj   +1 more source

Towards Fully Automated Segmentation of Rat Cardiac MRI by Leveraging Deep Learning Frameworks [PDF]

arXiv, 2021
Automated segmentation of human cardiac magnetic resonance datasets has been steadily improving during recent years. However, these methods are not directly applicable in preclinical context due to limited datasets and lower image resolution. Successful application of deep architectures for rat cardiac segmentation, although of critical importance for ...
arxiv  

Significance of Electrocardiographic QTc Interval on Assessment of Left Ventricular Diastolic Dysfunction in Hypertensive Patient: A Simple Screening Tool [PDF]

, 2019
Background: Diastolic dysfunction as part of heart failure with preserved ejection fraction (HFpEF) has gain interests, due to the increasing prevalence rate and poor prognosis.
Akbar, Nizam, Andra, Cut Aryfa, Hasan, Harris, Hasan, Refli, Putri, Sheila Dhiene, Siregar, A. Afif   +5 more
core   +2 more sources

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

Advanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, JoJo J. Holm, Quincy P. Lyons, Michael B. Nguyen, Jervaughn D. Hunter, Assa Magassa, Elyse G. Wong, Kate Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin G. Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
wiley   +1 more source

On in-silico estimation of left ventricular end-diastolic pressure from cardiac strains [PDF]

2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1-4
Left ventricular diastolic dysfunction (LVDD) is a group of diseases that adversely affect the passive phase of the cardiac cycle and can lead to heart failure. While left ventricular end-diastolic pressure (LVEDP) is a valuable prognostic measure in LVDD patients, traditional invasive methods of measuring LVEDP present risks and limitations ...
arxiv   +1 more source