Results 131 to 140 of about 2,930,669 (250)

Mechanisms and Management of Acquired Aseptic Intracardiac Communications After Transcatheter Aortic Valve Implantation: Single‐Center Case Series Insights

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Acquired aseptic intracardiac communications (AICCs) are rare but clinically relevant structural complications following transcatheter aortic valve implantation (TAVI), typically resulting from mechanical injury to the aortic annulus, interventricular septum, or adjacent structures.
Geza Fontos   +6 more
wiley   +1 more source

Biventricular Pressure‐Volume Loop Analysis in an LVAD Patient Optimized With Impella RP Flex

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Right ventricular (RV) failure after left ventricular assist device (LVAD) implantation is a serious complication which may necessitate temporary mechanical support in refractory cases. Here we describe a 63‐year‐old man with end‐stage ischemic cardiomyopathy and severe combined pre‐ and post‐capillary pulmonary hypertension who developed ...
Sara S. Inglis   +3 more
wiley   +1 more source

Cardiovascular prognosis in patients with preserved left ventricular ejection fraction and no significant ischemia

open access: yes, 2017
Tatsuhiko Furuhashi, Masao Moroi Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan Background: Peripheral artery disease (PAD) and chronic kidney disease (CKD) are important cardiac risk factors, and stress ...
Moroi M, Furuhashi T
core  

Diagnostic Agreement and Threshold Correspondence Between Resting Full‐Cycle Ratio and Nicorandil‐Based Fractional Flow Reserve in Intermediate Coronary Stenosis: A Prospective Single‐Center Registry

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background RFR has shown good aggregate agreement with FFR, including in prior Asian cohorts using intracoronary nicorandil. Where RFR‐FFR disagreement is concentrated relative to the FFR 0.80 decision boundary, and how the two binary thresholds correspond, remain incompletely characterized. Methods In a prospective single‐center registry, 300
Yonghoon Shin   +8 more
wiley   +1 more source

Siblings With Duchenne Muscular Dystrophy: Exploring Diagnosis Age and Disease Progression in a Genetic Therapy‐Naïve Cohort

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Duchenne muscular dystrophy (DMD) is the most common pediatric muscular dystrophy. Typically, there is a ~ 2‐year delay between symptom onset and diagnosis. Limited data on outcomes in early‐diagnosed individuals have limited the understanding of the clinical impact of early diagnosis.
Vaishnavi Brahmamdam   +8 more
wiley   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho   +12 more
wiley   +1 more source

In Silico Clinical Trials in Drug Development: Virtual Patients, Applications, and Regulatory Convergence

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Conventional clinical trials remain the benchmark for evaluating therapeutic safety and efficacy, yet they are constrained by escalating costs, withdrawal over the extended follow‐up periods, recruitment difficulties, ethical limits, and a restricted ability to characterize heterogeneous populations.
Maximilian Balmus   +7 more
wiley   +1 more source

In-Hospital Improved Left Ventricular Ejection Fraction and Prognosis in Acute Heart Failure. [PDF]

open access: yesJ Am Heart Assoc
Cocianni D   +13 more
europepmc   +1 more source

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