Results 221 to 230 of about 555,285 (355)

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Depressive state on cardiac remodeling and left ventricular function in chronic heart failure: A retrospective study. [PDF]

World J Psychiatry
Gao B, Gao YF, Chu MT, Yuan KF.
europepmc   +1 more source

852 Quantification of regional left ventricular function by real-time 3D echocardiography: validation by magnetic resonance imaging and clinical utility [PDF]

, 2005
Cristiana Corsi, Lissa Sugeng, H.-J. Nesser, Lynn Weinert, Johannes Niel, Christian Ebner, Roberto M. Lang, Victor Mor‐Avi   +7 more
openalex   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

Initial investigations into single nucleotide polymorphisms and their association with QTc and left ventricular function in peripartum cardiomyopathy. [PDF]

Eur J Heart Fail
Shaboodien G, Viljoen C, Ndibangwi P, Hoevelmann J, Pearce L, Haidari S, Torchio M, Dagradi F, Spazzolini C, Kraus S, Ntusi NAB, Schwartz PJ, Sliwa K.   +12 more
europepmc   +1 more source

Relationship between Baseline Right Ventricular Systolic Function and Left Ventricular Recovery at Six-Months of Follow Up Among Women with Peripartum Cardiomyopathy in Uganda

Juliet Nabbaale, Emmy Okello, Annettee Nakimuli, Graham Chakafana, Karen Sliwa   +4 more
openalex   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

The use of echocardiography to identify acute and chronic changes in left ventricular function in hypertensive disorder of pregnancy. [PDF]

BMC Pregnancy Childbirth
de Medeiros Lima RL, de Azevedo Cortez EG, Fidelis CR, de Lima LN, Mamere EC, Rego RA, de Lima JG, Jeronimo SMB.   +7 more
europepmc   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Assessment of left ventricular function

Cleveland Clinic Journal of Medicine, 1978
openaire   +2 more sources