Results 221 to 230 of about 8,700,013 (290)

A hybrid spatial and temporal attention driven network for left ventricular function assessment using echocardiography. [PDF]

Sci Rep
Batool S, Ghafoor M, Ahmad Taj I, Abdul W.   +3 more
europepmc   +1 more source

Cardiac Endothelial Enhancer RNA Tek‐e1 Restores Microvascular Homeostasis After Myocardial Infarction

Advanced Science, EarlyView.
Hypoxia‐induced KDM5A downregulation establishes a distinct endothelial repair programme, increasing H3K4me3 at the Tek promoter and intronic enhancer, enabling ISL1 to coordinately activate Tek transcription and induce enhancer‐RNA Tek‐e1. This cis‐regulatory RNA is essential for additional Tek/TIE2 induction through R‐loop formation and reinforced ...
Yang Lyu, Kun Yang, Yunzhi Ling, Jiahui Cheng, Jiaran Shi, Shiyu Hu, Changyi Zhou, Wei Wei, Hanchuan Chen, Xiang Wei, Zengru Wang, Zhi Xiong, Chenxi Yang, Su Zou, Rui Shen, Yuanyue Song, Gaofeng Zhang, Rifeng Gao, Kaiyang Lin, Yingjia Xu   +19 more
wiley   +1 more source

Effects of body mass index on left ventricular function: An echocardiographic comparison between obese and nonobese individuals. [PDF]

Physiol Rep
Kashem N, Ahmed F, Tanu S, Rahman A, Sultana R, Jui Y, Asaduzzaman M.   +6 more
europepmc   +1 more source

SynAtlas: A Safe and Versatile Platform for Rapid Organ‐Scale Tissue Clearing and 3D Atlas Mapping

Advanced Science, EarlyView.
An orthogonal synergy design principle integrates lipid solubilization, protein hydration modulation, and refractive‐index matching within a unified aqueous clearing system. This modular strategy enables rapid, low‐hazard, and broadly compatible tissue clearing while preserving molecular signals, supporting multiscale three‐dimensional imaging across ...
Mei‐Xue Yuan, Xin‐Ya Qin, Ling‐Jie Li, Kai‐Lang Xiao, Meng‐Meng Zhang, Kun‐Qi Chen, Peng Chen, Yu Wang, Chen‐Wei Wang, Nan Zhou, Qing‐Hong Shan   +10 more
wiley   +1 more source

The impact of heart rate on echocardiographic measures of left ventricular function: novel insights facilitated by deep learning. [PDF]

Eur Heart J Imaging Methods Pract
Woelfert A, Mjølstad OC, Dale AC, Salvesen Ø, Lovstakken L, Dalen H, Østvik A, Grenne B.   +7 more
europepmc   +1 more source

Targeting a Calcium‐Associated Mitochondrial Vulnerability in TET2‐Deficient Myeloid Cells

Advanced Science, EarlyView.
Reduced TET2 function creates a calcium‐associated mitochondrial vulnerability in macrophages that is preferentially exploited by Lanatoside C. The resulting stress promotes apoptosis of TET2‐deficient macrophages, reduces inflammatory and fibrotic injury in human cardiac organoids, and highlights a genotype‐associated myeloid liability that may be ...
Yue Wang, Minh Duc Pham, Despina Stefanoska, Ting Yuan, Arka Provo Das, Chaonan Zhu, Meiqian Wu, Thanh Thuy Duong, Jaskiran Kaur, Yu Hao, Johannes Krefting, Marius Schwab, Jonathan Ward, Maria Duda, Wesley Abplanalp, Moritz von Scheidt, Andreas M. Zeiher, Stefanie Dimmeler, Jaya Krishnan   +18 more
wiley   +1 more source

First-phase ejection fraction as a potential early indicator for left ventricular function in cardiac amyloidosis. [PDF]

Quant Imaging Med Surg
Huang T, Su C, Jiang C, Zeng D, Cai Y, Zhang X, Chang S, Luo J, Wu J.   +8 more
europepmc   +1 more source

A Single Volatile VO2 Memristor Enabling Neuromorphic Perception, Learning, and Computing

Advanced Electronic Materials, EarlyView.
A single volatile VO2 memristor fabricated via atomic layer deposition is demonstrated as a multifunctional neuromorphic device enabled by intrinsic threshold‐switching dynamics. The device reproduces neuron‐like integration and firing, short‐timescale associative learning, temporal ECG pattern classification, and nociceptive responses to electrical ...
Bingkai Ding, Bohao Ding, Omesh Kapur, Yisong Han, Richard Beanland, Kai Sun, C. H. (Kees) de Groot, Ruomeng Huang   +7 more
wiley   +1 more source

Rare Differentiation in Genes XIRP1 and XIRP2 Associated With Hypertrophic Cardiomyopathy

AGING MEDICINE, EarlyView.
XIRP2, but not XIRP1, acts as a key genetic modifier in hypertrophic cardiomyopathy (HCM). Rare variants in XIRP2 are enriched in patients and lead to dramatic mRNA overexpression (> 9‐fold, p < 0.001). Functionally, this disrupts intercalated disc integrity.
Fang Wang, Tao Yuan, Wenna Zhao, Guili Shao, Shuping Li, Lingyan Lv, Rong Li, Jie Liu, Xiaoyun Li, Wennan Wang, Fusong Liu, Xingfu Shang, Song Hu   +12 more
wiley   +1 more source

Longitudinal Displacement for Left Ventricular Function Assessment. [PDF]

J Cardiovasc Dev Dis
Leitman M, Tyomkin V.
europepmc   +1 more source