Results 41 to 50 of about 555,285 (355)

Statins and Left Ventricular Function

Current Pharmaceutical Design, 2018
Background: Statins are a well-established class of drugs in both preventing coronary events and treating cardiovascular atherosclerotic disease, however their use in heart failure is still in debate. </P><P> Objectives: To establish whether statins&#39; pleiotropic actions in endothelium, inflammation, remodeling of the heart and ...
Bakakos, Agamemnon, Oikonomou, Evangelos, Vogiatzi, Georgia, Siasos, Gerasimos, Tsalamandris, Sotiris, Antonopoulos, Alexios, Mourouzis, Costas, Fountoulakis, Petros, Vavuranakis, Manolis, Tousoulis, Dimitris   +9 more
openaire   +3 more sources

Mass and Left Ventricular Function in Protein Energy Malnutrion Marasmic Type

Majalah Kardiologi Indonesia, 2013
Objectives. To determine the left ventricular mass, the left ventricular systolic anddiastolic function of children suffering protein energy malnutrion marasmic type. Material.Pediatric patients suffering protein energy malnutrion marasmic type who came
Herlina Dimiati, Sudigdo Sastroasmoro, Sukman Tulus Putra, Aryono Hendarto   +3 more
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Longitudinal Displacement for Left Ventricular Function Assessment. [PDF]

J Cardiovasc Dev Dis
Background: Quantitative evaluation of myocardial function traditionally relies on parameters such as ejection fraction and strain. Strain, reflecting the relative change in the length of a myocardial segment over the cardiac cycle, has been extensively ...
Leitman M, Tyomkin V.
europepmc   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Effects of vildagliptin on ventricular function in patients with type 2 diabetes mellitus and heart failure: a randomized placebo-controlled trial [PDF]

, 2017
Objectives: This study sought to examine the safety of the dipeptidyl peptidase-4 inhibitor, vildagliptin, in patients with heart failure and reduced ejection fraction.
Bolli, Geremia B., Kothny, Wolfgang, Kozlovski, Plamen, Krum, Henry, Lewsey, James D., Lukashevich, Valentina, McMurray, John J.V., Ponikowski, Piotr   +7 more
core   +2 more sources

Evaluation of left ventricular function in patients with chronic obstructive pulmonary disease with or without pulmonary hypertension

Egyptian Journal of Chest Disease and Tuberculosis, 2013
Background: Chronic obstructive pulmonary disease (COPD) is a common entity in clinical practice. Development of right ventricular hypertrophy and eventual right side heart failure is also common in such patients.
Rabab A. El Wahsh, Mahmoud K. Ahmed, Rehab I. Yaseen   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Evidence that conflict regarding size of haemodynamic response to interventricular delay optimization of cardiac resynchronization therapy may arise from differences in how atrioventricular delay is kept constant. [PDF]

, 2014
Aims: Whether adjusting interventricular (VV) delay changes haemodynamic efficacy of cardiac resynchronization therapy (CRT) is controversial, with conflicting results.
Francis, DP, Hughes, AD, Jones, S, Kanagaratnam, P, Kyriacou, A, Manisty, CH, Mayet, J, Peters, NS, Sohaib, SM, Whinnett, ZI   +9 more
core   +2 more sources

Improvement of left ventricular systolic function after intervention on right ventricular hemodynamics

Annals of Pediatric Cardiology
Background: The importance of right–left ventricular interactions is increasingly recognized in patients with congenital heart disease. Interventions to improve right ventricular volume/pressure overloading may result in improvement of left ventricular ...
James Wiley, Whitney Fairchild, Anudeep K. Dodeja, Cesar I. Mesia, Caitlin M. Heyden, Shailendra Upadhyay   +5 more
doaj   +1 more source