Results 91 to 100 of about 198,729 (300)
Animal Models and Experimental Medicine, EarlyView.This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei +9 more
wiley +1 more source
Zdravniški Vestnik, 2004 Background. The heart is a target organ in arterial hypertension. Echocardiography is the most valuable noninvasive method to assess the left ventricular hypertrophy.
Marija Petek Šter, Boris Krajačič
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Cardiovascular Ultrasound, 2006 Background Cardiovascular risk associated with diabetes may be partially attributed to left ventricular structural abnormalities. However, the relations between left ventricular structure and diabetes have not been extensively studied in African ...
Liebson Philip R +6 more
doaj +1 more source
Animal models of chronic thromboembolic pulmonary hypertension
Animal Models and Experimental Medicine, EarlyView.Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu +5 more
wiley +1 more source
Angiotensin II type 2 receptors and cardiac hypertrophy in women with hypertrophic cardiomyopathy [PDF]
, 2001 The development of left ventricular hypertrophy in subjects with hypertrophic cardiomyopathy (HCM) is variable, suggesting a ...
Cate, F.J. (Folkert) ten +4 more
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Silencing of the Na+/H+ exchanger 1(NHE-1) prevents cardiac structural and functional remodeling induced by angiotensin II [PDF]
, 2019 Chronic activation of the renin angiotensin system (RAS) favors several cardiac diseases, among which myocardial hypertrophy occupies an outstanding place. In this context, the hyperactivity of the cardiac Na+/H+ (NHE-1) exchanger plays a key role.
Caldiz, Claudia Irma +4 more
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Equine models in translational medicine: A comparative approach to human health
Animal Models and Experimental Medicine, EarlyView.This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
Screening for Fabry Disease in Left Ventricular Hypertrophy: Documentation of a Novel Mutation
Arquivos Brasileiros de Cardiologia, 2015 Background: Fabry disease is a lysosomal storage disease caused by enzyme α-galactosidase A deficiency as a result of mutations in the GLA gene. Cardiac involvement is characterized by progressive left ventricular hypertrophy.
Ana Baptista +5 more
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Animal Models and Experimental Medicine, EarlyView.Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma +2 more
wiley +1 more source
Non-invasive electrical markers in patients with left ventricular hypertrophy.
Revista Cubana de Cardiología y Cirugía Cardiovascular, 2011 Introduction The left ventricular hypertrophy is related with the genesis of ventricular arrhythmiasand sudden death. Depending of the cause, different histologycalmodifications that generate different arrhythmogenic substrates, takesplace.
Nadia Sánchez Torres +5 more
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