ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Systemic Metabolic Rewiring in a Mouse Model of Left Ventricular Hypertrophy. [PDF]
Schmidt AV +6 more
europepmc +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Development and validation of an echocardiographic nomogram for identifying cardiac amyloidosis in patients with left ventricular hypertrophy. [PDF]
Liang S +8 more
europepmc +1 more source
Evolving Features of RASopathies Among Pregnancies With Abnormal Fetal Fluid Collections
ABSTRACT Objective We aimed to characterize the fetal features across gestation and describe genotype‐phenotype correlations for pregnancies with fetal RASopathies that were more severely affected as they presented with at least one abnormal fluid collection.
Natalie B. Gulrajani +17 more
wiley +1 more source
Computational modelling of the impact of anatomical changes on ECGs in left ventricular hypertrophy. [PDF]
Kariman M +5 more
europepmc +1 more source
Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress [PDF]
Michel Kindo +9 more
openalex +1 more source
Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan +10 more
wiley +1 more source
Clinically interpretable electrovectorcardiographic machine learning criteria for the detection of echocardiographic left ventricular hypertrophy. [PDF]
De la Garza-Salazar F, Egenriether B.
europepmc +1 more source

