Results 61 to 70 of about 208,685 (341)

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

open access: yes, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao   +80 more
core   +2 more sources

Left ventricular hypertrophy in athletes [PDF]

open access: yesEuropean Journal of Echocardiography, 2009
Participation in regular intensive exercise is associated with a modest increase in left ventricular wall thickness (LVWT) and cavity size. The magnitude of these physiological changes is predominantly determined by a variety of demographic factors which include age, gender, size, ethnicity, and sporting discipline.
John, Rawlins   +2 more
openaire   +2 more sources

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu   +13 more
wiley   +1 more source

Heart rate variability and target organ damage in hypertensive patients [PDF]

open access: yes, 2012
Background: We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).
2003 European Society of Hypertension   +56 more
core   +4 more sources

FGF23 induces left ventricular hypertrophy [PDF]

open access: yesJournal of Clinical Investigation, 2011
Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of cardiovascular disease in individuals with CKD. Elevated levels of FGF23 have been linked to greater risks of LVH and mortality in patients with CKD, but whether these risks
Christian, Faul   +34 more
openaire   +2 more sources

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

open access: yesAdvanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu   +10 more
wiley   +1 more source

PREVALENCE OF LEFT VENTRICULAR HYPERTROPHY IN NEWLY DIAGNOSED HYPERTENSIVE PATIENTS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To detect frequency of left ventricular hypertrophy in patients with newly diagnosed hypertension. Study Design: Cross sectional study. Place and Duration of Study: Out patient and inpatient, Department of Medicine of Combined Military ...
Umair Masood   +5 more
doaj  

HUBUNGAN HIPERTENSI DAN DIABETES MELLITUS DENGAN HIPERTROFI VENTRIKEL KIRI PADA PASIEN YANG MENJALANI HEMODIALISIS KRONIK DI RSUDZA BANDA ACEH [PDF]

open access: yes, 2017
ABSTRAKLatar Belakang: Hipertrofi ventrikel kiri (HVK) merupakan salah satu komplikasi gagal ginjal kronik (GGK) terbanyak, lebih dari 50% kematian penderita gagal ginjal kronik disebabkan oleh hipertrofi ventrikel kiri.
Lilis Fazriah
core  

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

open access: yesAdvanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang   +22 more
wiley   +1 more source

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