Results 311 to 320 of about 729,297 (395)

A Novel Cardiac Computed Tomography‐Based Calcium Scoring System for Predicting the Use of Atherectomy Devices in Severely Calcified Coronary Lesions

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Cardiac computed tomography (CT) is a well‐established process used to diagnose coronary artery disease; however, its specific advantages in predicting the use of atherectomy devices during percutaneous coronary intervention (PCI) for moderate to severe calcified lesions remain to be determined.
Yasuhiro Nakano   +19 more
wiley   +1 more source

Aortic Dissection With Pseudoaneurysm Formation Masquerading as Pulmonary Embolism After Transcatheter Aortic Valve Replacement

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Transcatheter aortic valve replacement (TAVR) is a commonly performed procedure for the treatment of severe aortic stenosis. While it is generally considered a low‐risk procedure, one of the rare potentially life‐threatening complications includes aortic dissection.
Heather Wang   +3 more
wiley   +1 more source

The Use of Synaptic Extracellular Myo‐Inositol to Treat Developmental and Epileptic Encephalopathy

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective The developmental and epileptic encephalopathies (DEE) are associated with serious and lifelong neurological conditions and risk of early mortality. Here, we describe the chronic treatment of a boy with PLCB1‐related DEE with enteral myo‐inositol supplementation as an add‐on therapy to standard antiseizure medications that had been ...
E. Naomi Vos   +15 more
wiley   +1 more source

Mineralocorticoid Receptor Antagonism Prevents Aortic Plaque Progression and Reduces Left Ventricular Mass and Fibrosis in Patients With Type 2 Diabetes and Chronic Kidney Disease: The MAGMA Trial. [PDF]

open access: yesCirculation
Rajagopalan S   +18 more
europepmc   +1 more source

Continuous Intravenous Nimodipine Infusion With Ethanol as Carrier in Aneurysmal Subarachnoid Hemorrhage Does Not Result in Measurable Cerebral Ethanol Levels

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
An unimpaired neurological evaluation is essential for detecting delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH) patients. Nimodipine is currently the only drug approved for DCI prevention. Intravenous nimodipine infusion contains 23.7 vol% ethanol as an excipient, resulting in up to 45 g of ethanol being infused daily ...
Miriam M. Moser   +8 more
wiley   +1 more source

Population Pharmacokinetics and Exposure‐Response Analysis of First‐Line Osimertinib Plus Chemotherapy in Patients with EGFR‐Mutated Advanced NSCLC

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Osimertinib, a third‐generation, central nervous system‐active epidermal growth factor receptor‐tyrosine kinase inhibitor, potently and selectively inhibits epidermal growth factor receptor‐tyrosine kinase inhibitor sensitizing and T790M resistance mutations, with efficacy in epidermal growth factor receptor‐mutated non‐small cell lung cancer.
Jincheng Yang   +10 more
wiley   +1 more source

Gender differences in coronary artery size per 100 g of left ventricular mass in a population without cardiac disease

open access: gold, 2001
Nils Kucher   +5 more
openalex   +1 more source

Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak   +4 more
wiley   +1 more source

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