Results 71 to 80 of about 729,297 (395)

Analysis of left ventricular mass in untreated men and in men treated with agalsidase-β: data from the Fabry Registry

Genetics in Medicine, 2013
Purpose:The aim of this study was to evaluate the progression of left ventricular hypertrophy in untreated men with Fabry disease and to assess the effects of agalsidase-β (recombinant human α-galactosidase A) on left ventricular hypertrophy.Methods ...
D. Germain, F. Weidemann, Ademola K. Abiose, M. Patel, M. Cizmarik, J. Cole, D. Beitner‐Johnson, K. Bénistan, G. Cabrera, J. Charrow, I. Kantola, A. Linhart, K. Nicholls, M. Niemann, C. Scott, K. Sims, S. Waldek, D. Warnock, J. Strotmann   +18 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

[OP.2D.05] RELATIONSHIP OF OXIDATIVE STRESS WITH CARDIAC HYPERTROPHY IN HYPERTENSIVE PATIENTS [PDF]

, 2016
OBJECTIVE: Left ventricular hypertrophy is common in hypertensive patients. In these subjects increased oxidative stress has been observed. Our aim was to evaluate the association of biomarkers of both oxidative stress and inflammation with markers of ...
Altieri, D., Cerasola, G., Cottone, S., Guarino, L., Guarneri, M., Mule', G., Nardi, E.   +6 more
core   +1 more source

Lack of Reduction of Left Ventricular Mass in Treated Hypertension: The Strong Heart Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2013
Background Hypertensive left ventricular mass (LVM) is expected to decrease during antihypertensive therapy, based on results of clinical trials. Methods and Results We assessed 4‐year change of echocardiographic LVM in 851 hypertensive free‐living ...
G. de Simone, R. Devereux, R. Izzo, D. Girfoglio, Elisa Lee, B. Howard, M. Roman   +6 more
semanticscholar   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Normotensive offspring of hypertensive Nigerians have increased Left ventricular mass and abnormal geometric patterns

The Pan African Medical Journal, 2012
BACKGROUND:Reports have shown that normotensive offspring of hypertensive parents (OHP) are at increased risk of developing systemic hypertension (SH) and adverse cardiovascular events later in life. The pathological antecedents of this are thought to be
Philip Kolo, Emmanuel Sanya, James Ogunmodede, Ayodele Omotoso, Ayodele Soladoye   +4 more
doaj   +1 more source

Necropsy Validation of a Novel Method for Left Ventricular Mass Quantification in Porcine Transthoracic and Transdiaphragmal Echocardiography

Frontiers in Cardiovascular Medicine, 2022
IntroductionIncreased left ventricular mass (LVM) is one of the most powerful predictors of adverse cardiovascular events. Clinical evaluation requires reliable, accurate and reproducible echocardiographic LVM-quantification to manage patients.
Charlotte Burup Kristensen, Stefan Michael Sattler, Stefan Michael Sattler, Anniek Frederike Lubberding, Jacob Tfelt-Hansen, Jacob Tfelt-Hansen, Thomas Jespersen, Christian Hassager, Christian Hassager, Rasmus Mogelvang, Rasmus Mogelvang, Rasmus Mogelvang   +11 more
doaj   +1 more source

Association between Circulating Fibroblast Growth Factor 23, α-Klotho, and the Left Ventricular Ejection Fraction and Left Ventricular Mass in Cardiology Inpatients

PLoS ONE, 2013
Background Fibroblast growth factor 23 (FGF23), with its co-receptor Klotho, plays a crucial role in phosphate metabolism. Several recent studies suggested that circulating FGF23 and α-Klotho concentrations might be related to cardiovascular ...
Kensaku Shibata, Shu-ichi Fujita, H. Morita, Yusuke Okamoto, K. Sohmiya, M. Hoshiga, N. Ishizaka   +6 more
semanticscholar   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Isometric exercise-induced hemodynamic load strongly predicts left ventricular mass in hypertension [PDF]

, 2009
C
Chirinos, Julio, Ferrari, Victor, Gupta, Amit, Keane, Martin, Kirkpatrick, James, Segers, Patrick, Sutton, Martin St John, Swillens, Abigail, Wiegers, Susan   +8 more
core   +1 more source