Results 81 to 90 of about 179,739 (339)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

A successful management of late-presenting transposition with intact septum and severe coarctation of the aorta

SAGE Open Medical Case Reports, 2020
A 13-week-old baby was referred with dextrocardia, situs inversus, transposition of the great arteries, intact ventricular septum, patent foramen ovale , right aortic arch with severe preductal aortic coarctation and large patent ductus arteriosus.
Pribadi Wiranda Busro, Alvin Ariyanto Sani, Michael Caesario   +2 more
doaj   +1 more source

THE EFFECT OF ENDURANCE, RESISTANCE AND CONCURRENT TRAINING ON THE HEART STRUCTURE OF FEMALE STUDENTS [PDF]

, 2012
he aim of this study was to compare the effect of endurance, resistance and concurrent training on the heart structure. Thirty-nine untrained female students (mean age 24±2.58 yrs) were randomly divided into four groups: Control (C; n=9), Endurance (E; n=
Hamid Agha-Alinejad, Masoumeh Hosseini, Mghsoud Piri, Shokoufeh Haj-Sadeghi   +3 more
core  

Specifics of Left Ventricular Hypertrophy and Characteristic of Phenotypic Variants in Patients with Hypertrophic Cardiomyopathy

Архивъ внутренней медицины, 2023
Hypertrophic cardiomyopathy is characterized by genetic and phenotypic heterogeneity which manifests in different variants of localization and extent of myocardial hypertrophy.Aim: to evaluate specifics of left ventricular hypertrophy, the prevalence and
G. I. Ignatenko, G. G. Taradin, T. E. Kugler   +2 more
doaj   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Diagnostic Value of Electrocardiography Compared with Echocardiography in Measuring Left Ventricular Mass Index in Major Thalassemia Patients Over 10 Years of Age

Journal of Tehran University Heart Center, 2015
Background: Patients suffering from major beta thalassemia need frequent blood transfusions and, if not treated well, would be at risk of heart dysfunction.
Noormohammad Noori, Maziar Mahjoubifard, SeyedMostafa Alavi, Saeid Hosseini, Hamidreza Sanati, Yalda Mirmesdagh   +5 more
doaj  

Gender differences in cardiac left ventricular mass and function: clinical and experimental observations [PDF]

, 2014
Background: The aim of this study was to evaluate gender-associated impact on left ventricular mass (LVM) and on left ventricular function (LVF) in humans and rats with aging. Methods: Myocyte area and collagen volume fraction (CVF) were studied in rats.
Aiello, Ernesto Alejandro, Diaz, Alejandro, Ennis, Irene Lucia, Escudero, Eduardo Manuel, Orlowski, Alejandro, Pinilla, Oscar Andres   +5 more
core   +2 more sources

Ambulatory Blood Pressure and Left Ventricular Mass Index in Hypertensive Children [PDF]

Hypertension, 2002
To determine whether ambulatory blood pressure is more predictive of left ventricular hypertrophy than is casual blood pressure in hypertensive children, echocardiography and ambulatory blood pressure data from 37 untreated hypertensive children were analyzed.
Ronald J. Portman, Jonathan M. Sorof, Kathy Franco, Gina Cardwell   +3 more
openaire   +3 more sources

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

Advanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source