Results 131 to 140 of about 2,680,249 (282)

Successful negative inotropic treatment of acute left ventricular outflow tract obstruction by elongated mitral valve leaflet

, 2014
Elongated anterior mitral valve leaflet (EAMVL) has not been reported to cause left ventricular outflow tract obstruction (LVOTO) in the absence of left ventricular hypertrophy. We report the case of an elderly male patient who presented with acute heart
Yiannikas, John, Ranasinghe, Isuru, Ayoub, Chadi   +2 more
core   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Beta-blocker therapy for dynamic left-ventricular outflow tract obstruction

, 2001
Background: In a small but significant group of elderly patients who present with breathlessness, dynamic left-ventricular outflow tract obstruction (DLVOTO) may be responsible for symptom generation. The aim of our study was to investigate the effect of
Henein, Michael Y., Sharma, Rakesh, Henein, M.Y., Sharma, R., Coats, Andrew J. S., Duncan, Alison, Al-Nasser, Faisal, Anker, Stefan D., Duncan, A., O'Sullivan, Christine, O'Sullivan, C., Al Nasser, F., Anker, S.D., Coats, A.J.S.   +13 more
core   +1 more source

3D transparent technology displays the developmental patterns of ductus arteriosus morphology in chicken embryos before and after birth

Journal of Anatomy, EarlyView.
At the eighth week of human embryonic development, 3D transparent imaging enables clear visualization of the outflow tract's morphological features, revealing its anatomical components in detail. Abstract The ductus arteriosus (DA) is a critical fetal vascular structure that shunts blood from the pulmonary artery to the aorta, bypassing the non ...
Conghong Xu, Lidi Li, Xiu Wu, Yanli Zhang, Chuanye Wu, Juan Chen, Haihua Gao, Zhenglai Ma   +7 more
wiley   +1 more source

Perioperative anesthetic management of patients with hypertrophic cardiomyopathy for noncardiac surgery: A case series

Annals of Cardiac Anaesthesia, 2010
Hypertrophic cardiomyopathy with or without left ventricular outflow tract obstruction is characterized by asymmetric hypertrophy of the interventricular septum causing intermittent obstruction of the left ventricular outflow tract.
Sahoo Rajendra, Dash Sananta, Raut Pradeep, Badole Usha, Upasani Chitra   +4 more
doaj  

Recent Clinical Updates of Hypertrophic Cardiomyopathy and Future Therapeutic Strategies

Reviews in Cardiovascular Medicine
Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiomyopathy transmitted in an autosomal dominant manner to offspring. It is characterized by unexplained asymmetrical hypertrophy primarily affecting the left ventricle and ...
Mengya Zhao, Xianzhen He, Xinwen Min, Handong Yang, Wenwen Wu, Jixin Zhong, Hao Xu, Jun Chen   +7 more
doaj   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Transient Left Ventricular Outflow Tract Obstruction in an Elderly Patient Admitted with Takotsubo

A 68-year-old elderly individual presented with takotsubo cardiomyopathy, and echocardiography revealed left ventricular outflow tract obstruction with a substantial gradient, particularly exacerbated by the Valsalva maneuver.
Smitha AnilKumar, Waleed Khalid Abdullatef, Khaled Al Khodari   +2 more
core   +1 more source

Long‐term outcomes following modified Blalock–Taussig–Thomas shunt placement in 13 dogs with cyanotic congenital heart disease

Journal of Small Animal Practice, EarlyView.
Objectives To describe long‐term outcome and owner‐perceived quality of life in dogs with cyanotic congenital cardiac disease undergoing modified Blalock–Taussig–Thomas shunt procedure. Materials and Methods Medical records of dogs that underwent Blalock–Taussig–Thomas shunt between 2009 and 2025 at a small animal referral hospital were retrospectively
M. Rossanese, J. Hannabuss, D. Brockman
wiley   +1 more source

Incidental Finding of Isolated Accessory Mitral Valve Tissue in Two Adults

Clinical Case Reports
Accessory mitral valve tissue is a rare congenital anomaly often linked to the anterior mitral leaflet, diagnosed via echocardiography. It may cause left ventricular outflow tract obstruction, with prognosis depending on obstruction severity and regular ...
Zhaofen Wang, Fang Du, Hao Zhu, Yuzhe Song, Lijuan Huang, Yi Yan, Peng Chang   +6 more
doaj   +1 more source