Results 31 to 40 of about 129,350 (262)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Diagnostic Value of High-Sensitivity Troponin T for Subclinical Left Ventricular Systolic Dysfunction in Patients with Sepsis

Cardiology Research and Practice, 2021
Background. Left ventricular systolic dysfunction (LVSD) is common in sepsis. Speckle-tracking echocardiography (STE) is a useful emerging tool for evaluating the intrinsic left ventricular systolic function. High-sensitivity cardiac troponin T (hs-cTnT)
Pham Dang Hai, Nguyen Thanh Binh, Nguyen Hong Tot, Ha Manh Hung, Le Thi Viet Hoa, Nguyen Viet Quang Hien, Pham Nguyen Son   +6 more
doaj   +1 more source

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Natriuretic peptide vs. clinical information for diagnosis of left ventricular systolic dysfunction in primary care

BMC Family Practice, 2008
Background Screening of primary care patients at risk for left ventricular systolic dysfunction by a simple blood-test might reduce referral rates for echocardiography.
Wachter Rolf, Pouwels Claudia, Kleta Sibylle, Wetzel Dirk, Kochen Michael M, Lüers Claus, Scherer Martin, Koschack Janka, Herrmann-Lingen Christoph, Pieske Burkert, Binder Lutz   +10 more
doaj   +1 more source

Left Ventricular Systolic Dysfunction [PDF]

Hypertension, 2010
Patients who enter into the most advanced phase of chronic kidney disease, that is, end-stage renal disease (ESRD), show an exceptionally high risk. Although the proportion of patients dying because of cardiovascular disease in this population does not differ from the corresponding proportion in the general population,1 the absolute risk for all-cause ...
openaire   +2 more sources

Myocardial strain to detect subtle left ventricular systolic dysfunction [PDF]

European Journal of Heart Failure, 2016
In daily clinical practice, LV systolic function is routinely assessed with the use of two‐dimensional echocardiography. Using biplane LV end‐diastolic and end‐systolic volumes, LVEF is calculated. The introduction of real‐time three‐dimensional echocardiography has improved the accuracy of echocardiographic assessment of LVEF. However, calculated LVEF
Tops, L.F., Delgado, V., Marsan, N.A., Bax, J.J.   +3 more
openaire   +3 more sources

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

Advanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour, Daniel Cohn, Ishita Sarkar, Raja Alamore, Kareem Abd Rbo, Offer Amir, Dean Nachman   +6 more
wiley   +1 more source

The effect of Valsalva maneuver on diastolic filling indices in patients with essential hypertension.

مجلة كلية الطب, 2010
Background: Left ventricular hypertrophy and diastolic dysfunction are considered to be an important risk factor for cardiovascular morbidity and mortality in asymptomatic hypertensive patients.
Salam A. Mahdi, Najeeb H. Mohammed, Hilal B. AL-Saffar   +2 more
doaj   +1 more source

Arterial wave reflection and subclinical left ventricular systolic dysfunction [PDF]

Journal of Hypertension, 2011
Increased arterial wave reflection is a predictor of cardiovascular events and has been hypothesized to be a cofactor in the pathophysiology of heart failure. Whether increased wave reflection is inversely associated with left-ventricular (LV) systolic function in individuals without heart failure is not clear.Arterial wave reflection and LV systolic ...
Cesare, Russo, Zhezhen, Jin, Yasuyoshi, Takei, Takuya, Hasegawa, Shun, Koshaka, Vittorio, Palmieri, Mitchell Sv, Elkind, Shunichi, Homma, Ralph L, Sacco, Marco R, Di Tullio   +9 more
openaire   +2 more sources