Results 111 to 120 of about 772,279 (379)

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim   +12 more
wiley   +1 more source

ASB1 differential methylation in ischaemic cardiomyopathy. Relationship with left ventricular performance in end stage heart failure patients [PDF]

open access: yesarXiv, 2017
Aims: Ischaemic cardiomyopathy (ICM) leads to impaired contraction and ventricular dysfunction causing high rates of morbidity and mortality. Epigenomics allows the identification of epigenetic signatures in human diseases. We analyse the differential epigenetic patterns of ASB gene family in ICM patients and relate these alterations to their ...
arxiv  

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

open access: yesAdvanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu   +18 more
wiley   +1 more source

Real-time Assessment of Right and Left Ventricular Volumes and Function in Children Using High Spatiotemporal Resolution Spiral bSSFP with Compressed Sensing [PDF]

open access: yesarXiv, 2018
Background: Real-time (RT) assessment of ventricular volumes and function enables data acquisition during free-breathing. However, in children the requirement for high spatiotemporal resolution requires accelerated imaging techniques. In this study, we implemented a novel RT bSSFP spiral sequence reconstructed using Compressed Sensing (CS) and ...
arxiv  

A Dual‐Modal Wearable Pulse Detection System Integrated with Deep Learning for High‐Accuracy and Low‐Power Sleep Apnea Monitoring

open access: yesAdvanced Science, EarlyView.
A dual‐modal wearable pulse detection system is developed for sleep apnea monitoring by integrating a self‐powered PENG and PPG sensor with a biomimetic fingertip structure. Through a two‐stage detection strategy, continuous PPW monitoring and on‐demand PPG detection achieve high‐accuracy sleep apnea recognition while maintaining low power consumption.
Jia Wang   +10 more
wiley   +1 more source

PECULIAR FEATURES IN STRUCTURAL AND FUNCTIONAL HEART VALUES IN PERSONS WITH VARIOUS LEVELS OF BLOOD PRESSURE

open access: yesРоссийский кардиологический журнал, 2002
113 healthy subjects with normal blood pressure and 26 patients with essential hypertension (BP 140-159/90-99 mm Hg) were inspected by echocardiography. All subjects were divided into 5 groups according to the blood pressure (BP) level.
A. V. Tuyev, Y. B. Hovayeva
doaj  

Left ventricular torsion rate and the relation to right ventricular function in pediatric pulmonary arterial hypertension

open access: yesPulmonary Circulation, 2018
The right ventricle and left ventricle are physically coupled through the interventricular septum. Therefore, changes in the geometry and mechanics of one ventricle can directly affect the function of the other.
Melanie J. Dufva   +5 more
doaj   +1 more source

The pathophysiology of diastolic heart failure [PDF]

open access: yes, 2010
Whilst resting disturbances of both diastolic and long-axis systolic function are observed in patients with heart failure who have normal left ventricular ejection fraction, recent evidence suggests that dynamic disturbances in cardiac function occur ...
Frenneaux, Michael, Phan, Thanh Trung
core   +3 more sources

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

open access: yesAdvanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan   +16 more
wiley   +1 more source

Prevalence, correlates, effects and detection of left ventricular systolic dysfunction in an urban population [PDF]

open access: yes, 1999
The prevalence of chronic heart failure (CHF) in most epidemiological studies has been determined by using clinical criteria.In this thesis, in contrast, left ventricular systolic function was assessed objectively by echocardiography in a cross ...
McDonagh, Theresa A.
core   +1 more source

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