Results 111 to 120 of about 772,279 (379)
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim+12 more
wiley +1 more source
ASB1 differential methylation in ischaemic cardiomyopathy. Relationship with left ventricular performance in end stage heart failure patients [PDF]
Aims: Ischaemic cardiomyopathy (ICM) leads to impaired contraction and ventricular dysfunction causing high rates of morbidity and mortality. Epigenomics allows the identification of epigenetic signatures in human diseases. We analyse the differential epigenetic patterns of ASB gene family in ICM patients and relate these alterations to their ...
arxiv
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu+18 more
wiley +1 more source
Real-time Assessment of Right and Left Ventricular Volumes and Function in Children Using High Spatiotemporal Resolution Spiral bSSFP with Compressed Sensing [PDF]
Background: Real-time (RT) assessment of ventricular volumes and function enables data acquisition during free-breathing. However, in children the requirement for high spatiotemporal resolution requires accelerated imaging techniques. In this study, we implemented a novel RT bSSFP spiral sequence reconstructed using Compressed Sensing (CS) and ...
arxiv
A dual‐modal wearable pulse detection system is developed for sleep apnea monitoring by integrating a self‐powered PENG and PPG sensor with a biomimetic fingertip structure. Through a two‐stage detection strategy, continuous PPW monitoring and on‐demand PPG detection achieve high‐accuracy sleep apnea recognition while maintaining low power consumption.
Jia Wang+10 more
wiley +1 more source
113 healthy subjects with normal blood pressure and 26 patients with essential hypertension (BP 140-159/90-99 mm Hg) were inspected by echocardiography. All subjects were divided into 5 groups according to the blood pressure (BP) level.
A. V. Tuyev, Y. B. Hovayeva
doaj
The right ventricle and left ventricle are physically coupled through the interventricular septum. Therefore, changes in the geometry and mechanics of one ventricle can directly affect the function of the other.
Melanie J. Dufva+5 more
doaj +1 more source
The pathophysiology of diastolic heart failure [PDF]
Whilst resting disturbances of both diastolic and long-axis systolic function are observed in patients with heart failure who have normal left ventricular ejection fraction, recent evidence suggests that dynamic disturbances in cardiac function occur ...
Frenneaux, Michael, Phan, Thanh Trung
core +3 more sources
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan+16 more
wiley +1 more source
Prevalence, correlates, effects and detection of left ventricular systolic dysfunction in an urban population [PDF]
The prevalence of chronic heart failure (CHF) in most epidemiological studies has been determined by using clinical criteria.In this thesis, in contrast, left ventricular systolic function was assessed objectively by echocardiography in a cross ...
McDonagh, Theresa A.
core +1 more source