Results 61 to 70 of about 253,881 (304)

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Early assessment of percutaneous coronary interventions for chronic total occlusions analyzed by novel echocardiographic techniques

Clinics, 2013
OBJECTIVE: Successful revascularization of chronic total occlusions has been associated with improved left ventricular systolic function, reduced anginal symptoms, increased exercise capacity, and increased survival. This study was conducted to determine
Ercan Erdogan, Mehmet Akkaya, Ahmet Bacaksiz, Abdurrrahman Tasal, Osman Sonmez, Mehmet Ali Elbey, Seref Kul, Mehmet Akif Vatankulu, Murat Turfan, Omer Goktekin   +9 more
doaj   +1 more source

Left ventricular systolic function in aortic stenosis [PDF]

, 2017
In aortic valve stenosis, concentric hypertrophy develops which is characterized by a reduced end-diastolic radius-to-wall thickness ratio (r/h) with an essentially normal cavity shape.
Hess, O. M., Hoppeler, H., Krayenbuehl, H. P., Monrad, E. S., Ritter, M.   +4 more
core  

Left ventricular midwall mechanics at 24 weeks' gestation in high-risk normotensive pregnant women: Relationship to placenta-related complications of pregnancy [PDF]

, 2012
Most studies during pregnancy have assessed maternal left ventricular (LV) function by load-dependent indices, assessing only chamber function. The aim of this study was to assess afterload-adjusted LV myocardial and chamber systolic function at 24 weeks'
Gagliardi, G, Giannini, L, Manfellotto, D, Novelli, GP, Pisani, I, Tiralongo, GM, Valensise, H, Vasapollo, B   +7 more
core   +1 more source

3D‐Printed Dynamic Heart Model With Left‐Side Anatomy and Integrated Sensor for Edge‐to‐Edge Repair and Regurgitation Reduction

Advanced Materials Technologies, EarlyView.
This work presents a fully synthetic, 3D‐printed dynamic heart model with left‐side anatomy featuring sutured mitral valve chordae tendineae analogs, embedded actuators for physiologic wall contraction, and customized flexible pressure sensors for the left ventricle.
Alejandro Guillen Obando, Hongyi Shen, Myles McGovern, Yusen Zhang, Vivien Lin, Darryl Fu, Ryan Baumwart, Kaiyan Qiu   +7 more
wiley   +1 more source

Treatment of chronic heart failure with a very low dose of antibodies to C-fragment of type 1 angiotensin II receptor

Бюллетень сибирской медицины, 2009
The open randomized placebo-controlled prospective study was conducted; we documented improvement of global contractility and diastolic function of left ventricle, clinical and psychological status in 60 patients with chronic heart failure receiving a ...
T. M. Poponina, Ye. S. Noll, Yu. S. Poponina, B. F. Portnyagin, N. M. Simonova   +4 more
doaj   +1 more source

Compensated right ventricular function of the onset of pulmonary hypertension in a rat model depends on chamber remodeling and contractile augmentation. [PDF]

, 2018
Right-ventricular function is a good indicator of pulmonary arterial hypertension (PAH) prognosis; however, how the right ventricle (RV) adapts to the pressure overload is not well understood.
Abe K, Alencar A, Arts T, Bellofiore A, Benoist D, Benoist D, Blaudszun G, Cheng DC, Correia-Pinto J, de Man FS, Ewalenko P, Gomez-Arroyo JG, Guccione JM, Handoko ML, Handoko ML, Hardy MEL, Hessel MHM, Hoeper MM, Langer SFJ, Lee LC, Pacher P, Provencher S, Rain S, Schermuly RT, Shintani H, ter Keurs HE, Trip P, Umar S, Vaillancourt M, Vanderpool RR, Vinnakota KC, Wang Z, Werchan PM, White RJ, Yin X, Zhang X   +35 more
core   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Effect of Peritoneal Dialysis Treatment on Left Ventricular Systolic and Diastolic Functions in Patients with End-Stage Renal Disease

Turkish Journal of Nephrology, 2019
OBJECTIVE: To analyze the effect of peritoneal dialysis (PD) treatment on left ventricular systolic and diastolic function in patients with end-stage renal disease (ESRD).
Feridun KAVUNCUOĞLU, Oktay OYMAK, Bülent TOKGÖZ, Murat Hayri SİPAHİOĞLU, Havva CİLAN, Nilüfer OĞUZHAN, Mesut AKÇAKAYA, İsmail KOÇYİĞİT, Mustafa DURAN, Mikail YARLIOĞLUEŞ, Aydın ÜNAL, Cengiz UTAŞ   +11 more
doaj  

Three-dimensional echocardiography and 2D-3D speckle tracking imaging in chronic pulmonary hypertension. diagnostic accuracy in detecting hemodynamic signs of RV failure [PDF]

, 2015
Background and objective. Our aim was to compare three-dimensional (3D) and 2D and 3D speckle tracking (2D-STE, 3D-STE) echocardiographic parameters with conventional right ventricular (RV) indexes in patients with chronic pulmonary hypertension (PH ...
Alessia, Azzano, Capotosto, Lidia, Gaudio, Carlo, Mangieri, Enrico, Nino, Cocco, Rasul, Ashurov, Rosato, Edoardo, Salsano, Felice, Simona, D’Orazio, Terzano, Claudio, Truscelli, Giovanni, Vitarelli, Antonino   +11 more
core   +1 more source