Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye+13 more
wiley +1 more source
The Role of Muscle Density in Predicting the Amputation Risk in Peripheral Arterial Disease: A Tissue Composition Study Using Lower Extremity CT Angiography. [PDF]
Lin YH+6 more
europepmc +1 more source
THE EFFECT OF APPLICATION OF TOURNIQUETS TO THE LEGS ON CARDIAC OUTPUT AND RENAL FUNCTION IN NORMAL HUMAN SUBJECTS 12 [PDF]
Francis W. Fitzhugh+4 more
openalex +1 more source
According to literatures, magnetoelastic soft materials have achieved a maximum magnetic flux change of 80%, making it difficult to enhance the magnetic flux change. To address this, this manuscript proposed a reversed magnetic field strategy in conjunction with logarithmic helical design and magnetoelastic deformation.
Xiaojun Chen+11 more
wiley +1 more source
Bacterial cell walls (CWs) extracted from Porphyromonas gingivalis are nanofabricated to form the CW vesicles (CWV), which have intrinsic peroxidase‐mimicking and sonodynamic activities due to the presence of µ‐oxo bisheme and meanwhile retain a large amount of lipopolysaccharide.
Meng Yang+9 more
wiley +1 more source
Corticomuscular coherence during upright standing in unilateral transfemoral amputees. [PDF]
Meyer B+12 more
europepmc +1 more source
The Immediate Influence of Increased Venous Pressure Upon Resistance to Flow in the Dog's Hind Leg [PDF]
Fred Phillips+2 more
openalex +1 more source
MGPT: A Multi‐task Graph Prompt Learning Framework for Drug Discovery
MGPT is a unified multi‐task graph prompt learning model providing generalizable and robust graph representations for few‐shot drug association prediction. MGPT demonstrates the ability of seamless task switching and outperforms competitive approaches in few‐shot scenarios.
Yang Li+4 more
wiley +1 more source
Design and Control of Bio-Inspired Joints for Legged Robots Driven by Shape Memory Alloy Wires. [PDF]
Niu X, Yao X, Dong E.
europepmc +1 more source
Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster+2 more
wiley +1 more source