Results 51 to 60 of about 1,220,871 (290)

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Neuroimaging biomarkers for predicting acupuncture treatment response in chronic pain: a systematic review and meta-analysis protocol

open access: yesBMJ Open
Introduction Acupuncture is increasingly recognised as an effective treatment for chronic pain conditions, yet inter-individual variability in treatment response remains a major clinical challenge.
Biao Wang   +6 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Propeller Perforator Flaps in Distal Lower Leg: Evolution and Clinical Applications

open access: yesArchives of Plastic Surgery, 2012
Simple or complex defects in the lower leg, and especially in its distal third, continue to be a challenging task for reconstructive surgeons. A variety of flaps were used in the attempt to achieve excellence in form and function.
Alexandru V. Georgescu
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Pilot Study: Fat Pad Restoration With Adipose Allograft in Metatarsalgia Patients Shows Structural, Functional Improvement

open access: yesPlastic and Reconstructive Surgery, Global Open
Background:. Metatarsalgia is a painful and debilitating condition that is often linked to plantar fat pad atrophy, particularly in active individuals and those with structural foot deformities.
Jodi Schoenhaus Gold, DPM, RPhs, FACFAS
doaj   +1 more source

Comparative Study of Traveling and Standing Wave-Based Locomotion of Legged Bidirectional Miniature Piezoelectric Robots

open access: yesMicromachines, 2021
The use of wave-based locomotion mechanisms is already well established in the field of robotics, using either standing waves (SW) or traveling waves (TW).
Jorge Hernando-García   +3 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Sustainable Development in the Tunisian Hotel Sector: A Case Study of Using LED Lighting and Photovoltaic Systems

open access: yesEnergies
Researchers and companies are placing increasing importance on sustainability to fight climate change. This study analyzes the sustainability of hotel installation, photovoltaic (PV) solar panels, and the transition from traditional lighting to light ...
Hedi Trabelsi, Younes Boujelbene
doaj   +1 more source

CD5+ Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type, Presenting as an Asymptomatic Nodule

open access: yesHematology Reports, 2023
Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), is a rare and aggressive variant of primary cutaneous lymphoma that typically expresses B cells as well as MUM1/IRF4, BCL2, and FOXP1, whereas BCL6 may be present or undetectable. We
Amy Xiao   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy