Results 71 to 80 of about 67,303 (311)

Editorial: Advancements in biomechanical modeling of injuries, diseases, diagnoses, and treatments of lower extremities

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Mohammad Nikkhoo   +6 more
doaj   +1 more source

METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis

open access: yesAdvanced Science, EarlyView.
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang   +13 more
wiley   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu   +17 more
wiley   +1 more source

Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
As an inevitable disease, muscle atrophy has received more attention. Because the factors that induce this disease are diverse, achieving a complete cure is still impossible. Wearable bioelectronics provides a more comfortable, low‐cost, and efficient way of home care for the monitoring and treatment of muscle atrophy. Therefore, this review summarizes
Shuai Zhang   +4 more
wiley   +1 more source

Trivial incident leading to tennis leg managed conservatively: A case report

open access: yesSAGE Open Medical Case Reports
Since 1883, “tennis leg” has described various acute calf injuries linked to activities such as tennis serving or stair climbing. Current research suggests that tennis leg is caused by the injury of the medial head of the gastrocnemius muscle.
Sugat Adhikari   +4 more
doaj   +1 more source

tRF‐5004b Enriched Secretory Autophagosomes Induce Endothelial Cell Activation to Drive Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu   +17 more
wiley   +1 more source

Acute hamstring injuries in rugby players: The influence of positioning during ice therapy on muscle length

open access: yesSouth African Journal of Physiotherapy, 1990
The effect on muscle length of positioning with ice application to acute hamstring injuries in rugby players was examined. Ice was applied with the hamstring muscle group in either the lengthened or the shortened position.
C. Becker   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy