Results 81 to 90 of about 67,303 (311)

A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds

open access: yesAdvanced Science, EarlyView.
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou   +7 more
wiley   +1 more source

Strong and Fatigue‐Resistant Hydrogels via Poor Solvent Evaporation Assisted Hot‐Stretching for Tendon Repair

open access: yesAdvanced Science, EarlyView.
An anisotropic hydrogel (AHs) is prepared in this study. The strength of AHs can reach up to 33.14 ± 2.05 MPa, and it exhibits unique defect‐insensitive characteristics. Cracks can only deflect along the fiber alignment direction, demonstrating an interesting self‐protection function.
Huamin Li   +11 more
wiley   +1 more source

Theranostic Toolbox for Neutrophil Functionalization

open access: yesAdvanced Science, EarlyView.
Here, neutrophil‐specific fluorine nanoparticles additionally equipped with either activating or inhibiting peptides for a background‐free 19F MRI‐based nanotheranostic approach are engineered. It is demonstrated that this approach is suitable to visualize and concomitantly direct neutrophil functionality depending on the specific requirements to ...
Pascal Bouvain   +11 more
wiley   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

open access: yesAdvanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai   +20 more
wiley   +1 more source

A companion to the preclinical common data elements for genomics, transcriptomics, and epigenomics data in rodent epilepsy models. A report of the TASK3‐WG4 omics working group of the ILAE/AES joint translational TASK force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines. The aim of the CDEs is to improve the standardization of experimental designs across a range of epilepsy ...
Erwin A. van Vliet   +11 more
wiley   +1 more source

Nanofabricated Bacterial Cell Walls with Intrinsic Peroxidase‐Mimicking and Sonodynamic Activities for Cancer Combination Treatment

open access: yesAdvanced Science, EarlyView.
Bacterial cell walls (CWs) extracted from Porphyromonas gingivalis are nanofabricated to form the CW vesicles (CWV), which have intrinsic peroxidase‐mimicking and sonodynamic activities due to the presence of µ‐oxo bisheme and meanwhile retain a large amount of lipopolysaccharide.
Meng Yang   +9 more
wiley   +1 more source

Is the addition of running retraining to best standard care beneficial in runners with medial tibial stress syndrome? Protocol for a randomised controlled trial

open access: yesJournal of Foot and Ankle Research
Background Running retraining is commonly used in the management of medial tibial stress syndrome (MTSS) but evidence for its effectiveness is lacking. The primary aim of this study is to determine if the addition of running retraining to best standard ...
Laura M. Anderson   +7 more
doaj   +1 more source

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