Results 81 to 90 of about 63,410 (305)

A Case of Pyoderma Gangrenosum [PDF]

, 2012
Case Report A 60-year-old man with past medical history of hypertension, post-traumatic stress disorder, major depression, hepatic steatosis, chronic kidney disease, and untreated hepatitis C virus (genotype 1b) initially presented to the outpatient ...
Miller, MD, Christopher T.
core   +2 more sources

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

Aging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda, Yosuke Inaba, Yuki Shiko, Yoshihito Ozawa, Vilhelm A. Bohr, Yoshiro Maezawa, Koutaro Yokote   +15 more
wiley   +1 more source

Novel Surgical Treatment for Refractory Heel Ulcers in Werner’s Syndrome

Case Reports in Orthopedics, 2013
Patients with Werner’s syndrome frequently develop chronic leg ulcers that heal poorly. We present a patient who suffered from this rare syndrome and developed typical heel ulcers.
Keisuke Oe, Masahiko Miwa, Yoshitada Sakai, Masahiro Kurosaka   +3 more
doaj   +1 more source

A Case of Malignant Melanoma with In-Transit Metastasis That Responded to Intravenous Infusion of Interferon-β

Case Reports in Dermatology, 2014
A 77-year-old man with a history of surgical resection of malignant melanoma involving the fifth toe of his left foot 14 years ago presented at the Kariya Toyota General Hospital with a 3-month history of skin ulcer at the same site and red nodules on ...
Masaru Arima, Youhei Iwata, Yusuke Morita, Tsukane Kobayashi, Ryousuke Sasaki, Kayoko Suzuki, Kayoko Matsunaga   +6 more
doaj   +1 more source

Using Biologics to Reduce Long‐Term Corticosteroid Use in Pyoderma Gangrenosum: Real‐World Evidence From Two Centres

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a challenging inflammatory skin disorder. While corticosteroids offer a rapid response, their long‐term risks necessitate alternative treatments. Objective To compare the long‐term effectiveness of biologic therapies versus systemic corticosteroids in PG management. Methods A retrospective analysis of 15
R. Cascio Ingurgio, A. Alfano, L. Gargiulo, L. Ibba, A. Narcisi, F. Satgé, M. Stark, A. Costanzo, D. F. Murrell   +8 more
wiley   +1 more source

Investigation of the effect of deprivation on the burden and management of venous leg ulcers: a cohort study using the THIN database.

PLoS ONE, 2013
BackgroundThere has been limited examination of the contribution of socio-economic factors to the development of leg ulcers, despite the social patterning of many underlying risk factors.
Emily S Petherick, Nicky A Cullum, Kate E Pickett   +2 more
doaj   +1 more source

Iron overload and morbidities in Chinese with non‐transfusion‐dependent thalassaemia

British Journal of Haematology, EarlyView.
A cross‐sectional study in Hong Kong included 109 adult and paediatric Chinese patients with non‐transfusion dependent thalassaemia (NTDT). The study found significant chronic health issues in 52% of patients. More severe disease was observed in patients with non‐deletional α‐thalassaemia intermedia, β‐thalassaemia intermedia, advanced age and history ...
Wing‐yan Leung, Tracy Yuen‐han Lee, Yu‐yan Hwang, Jasmine Tsz‐man Lee, Chun‐Fung Sin, Sio‐peng Mok, Chung‐yin Ha, Allen Li, Wendy Wai‐man Lam, Man‐fung Yuen, Yok‐lam Kwong, Dorine W. Swinkels, Coby M. Laarakkers, Daniel Ka‐leung Cheuk, Godfrey Chi‐fung Chan, Chak‐ho Li, Yiu‐fai Cheung, Chi Chiu So, Shau‐yin Ha, Anthony Pak‐yin Liu   +19 more
wiley   +1 more source

A Randomized, Controlled Clinical Study to Assess the Effect of Anodal and Cathodal Electrical Stimulation on Periwound Skin Blood Flow and Pressure Ulcer Size Reduction in Persons with Neurological Injuries [PDF]

, 2018
The use of electrical stimulation (ES) should be considered for treating nonhealing pressure ulcers (PUs), but optimal ES wound treatment protocols have yet to be established.
Blaszczak, Edward, Ficek, Krzysztof, Franek, Andrzej, Hordynska, Ewa, Ickowicz, Tomasz, Kloth, Luther C., Kucio, Cezary, Kucio, Ewa, Oleszczyk, Krystian, Paczula, Malgorzata, Polak, Anna   +10 more
core   +2 more sources

Value of combined exercise and ultrasound as an adjunct to compression therapy in chronic venous leg ulcers

Egyptian Rheumatology and Rehabilitation, 2017
Introduction Chronic venous leg ulcers are very difficult to treat and take very long time to heal. Compression therapy remains the mainstay of venous ulcer conservative treatment. Aim The aim of this study was to evaluate the effectiveness of combined
Rehab A.E Sallam, Atif I El Ghaweet, Samer A.H Regal   +2 more
doaj   +1 more source

Evolution of psychoanalytic approaches to somatic disorders

British Journal of Psychotherapy, EarlyView.
Abstract Initially, Freud proposed two distinctive ways of understanding somatic symptoms: the hysterical conversion and the actual neuroses models. The original conversion model posited that somatic symptoms had meaning and resulted from psychic mechanisms, whereas actual neuroses model proposed somatic symptoms had no meaning and resulted from ...
Jaime Yasky
wiley   +1 more source