Results 41 to 50 of about 753,619 (306)

Measuring costs and quality of life for venous leg ulcers

International Wound Journal, 2018
Venous leg ulcers (VLUs) result in substantial economic costs and reduced quality of life (QoL); however, there are few Australian cost estimates, especially using patient‐level data.
Louise Barnsbee, Qinglu Cheng, Ruth Tulleners, X. Lee, D. Brain, R. Pacella   +5 more
semanticscholar   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Evaluation of a composite skin substitute to treat venous stasis ulcers: a pilot study

Brazilian Journal of Transplantation, 2006
Introduction: Venous leg ulcers represent a therapeutic challenge, and they are associated to significant morbidity and cost. Many advances have been made to develop and apply biological skin substitutes, showing they can be beneficial for patients with
Paula Dadalti-Granja, Marco Aurélio Leiros, Bernardo M O Pascalleri, Christina Maeda Takyia, Radovan Borojevic, Renata Brum Martucci, Talita Franco, Marcia Ramos-e-Silva   +7 more
doaj   +1 more source

A multicentre randomised controlled trial evaluating the efficacy of dehydrated human amnion/chorion membrane (EpiFix®) allograft for the treatment of venous leg ulcers

International Wound Journal, 2017
A randomised, controlled, multicentre clinical trial was conducted to evaluate the efficacy of dehydrated human amnion/chorion membrane (EpiFix) allograft as an adjunct to multilayer compression therapy for the treatment of non‐healing full‐thickness ...
C. Bianchi, S. Cazzell, D. Vayser, A. Reyzelman, H. Dosluoglu, Gregory Tovmassian   +5 more
semanticscholar   +1 more source

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

Advanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi, Sang Won Lee, Mohammad Abrar Uddin, Sina Hassanpoor, Neha Suvindran, Katherine Le, Harun Arkaz, Harishkumar Narayana, Saeid Soltanian, Danial Khorsandi, Negar Hosseinzadeh Kouchehbaghi, Taeil Kim, Yangzhi Zhu   +12 more
wiley   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Machine learning model to classify chronic leg wounds and identify pyoderma gangrenosum

BMJ Health & Care Informatics
Study objectives Chronic wounds represent a significant economic and personal burden. For their successful treatment, the causes must be known and treated.
Carola Berking, Dorothee A Busch, Mats L Richter, Jens Hüsers, Mareike Przysucha, Florian Kücking, Jonathan M Mang, Maurice Moelleken, Joachim Dissemond, Jan Heggemann, Guido Hafer, Cornelia Erfurt-Berge, Ursula H Hübner   +12 more
doaj   +1 more source

Microfluidic Valve‐Integrated Garment for Smooth Sequential Gradient Mechanotherapy

Advanced Intelligent Systems, EarlyView.
We present a soft wearable sleeve that delivers smooth, gap‐free compression using overlapping air‐filled actuators and tiny microfluidic valves. The system reduces bulk, lowers power needs, and uses a smartphone‐sized control box. It can provide sequential gradient compression, gradient pressure holding, and fast deflation, supporting more portable ...
Run Ze Gao, Chen Xi Huang, Drew M. Werbowski, Jacqueline Mary Kormylo, Clark R. Dickerson, Carolyn L. Ren   +5 more
wiley   +1 more source

Investigation of the effect of deprivation on the burden and management of venous leg ulcers: a cohort study using the THIN database.

PLoS ONE, 2013
BackgroundThere has been limited examination of the contribution of socio-economic factors to the development of leg ulcers, despite the social patterning of many underlying risk factors.
Emily S Petherick, Nicky A Cullum, Kate E Pickett   +2 more
doaj   +1 more source