Results 31 to 40 of about 477,948 (309)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Legacy Meridian Park community health improvement plan
, 2021 Title from PDF cover (viewed on March 31, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Legacy Mount Hood community health improvement plan
, 2021 Title from PDF cover (viewed on March 31, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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Legacy System Anti-Patterns and a Pattern-Oriented Migration Response [PDF]
, 2000 Mature information systems grow old disgracefully as successive waves of hacking result in accidental architectures which resist the reflection of on-going business process change. Such petrified systems are termed legacy systems.
Lauder, Anthony +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Life, 2022 Dermatomyositis is a rare inflammatory myopathy that is often related to lung cancer. In this retrospective observational study, we analyzed data from patients diagnosed with lung cancer at Soroka University Medical Center between January 2017 and July ...
Walid Shalata +6 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Legacy Good Samaritan community health improvement plan
, 2021 Title from PDF cover (viewed on March 31, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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