Results 81 to 90 of about 477,948 (309)

The Role of Insulin and Insulin-like Growth Factors in the Increased Risk of Cancer in Diabetes

open access: yesRambam Maimonides Medical Journal, 2011
Patients with type 2 diabetes (T2D) are at increased risk of developing cancer. This evidence arises from numerous epidemiologic studies that relate a positive association between T2D and cancer. In-vitro and several in-vivo experiments have attempted to
Derek LeRoith   +2 more
doaj   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

open access: yesAdvanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li   +6 more
wiley   +1 more source

Prevalence of tooth loss among geriatrics of Amachalla, Igbo-Eze North L.G.A., Enugu State, Nigeria

open access: yesOrapuh Journal, 2021
Introduction Tooth loss is the loss of one tooth or more teeth due to trauma, disease, or extraction. Tooth loss, depending on the degree, may reduce speech and masticatory abilities (which in turn affects intake of nutrition), and may impair aesthetics.
VE Adamu   +2 more
doaj  

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

open access: yesAdvanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang   +3 more
wiley   +1 more source

Tevatron Legacy

open access: yesIl Nuovo Cimento C, 2012
6 pages, proceedings for the Top2011 conference, Sant Feliu de Guixols ...
openaire   +3 more sources

The Manhattan Legacy [PDF]

open access: yesAnaesthesia and Intensive Care, 2007
The Manhattan Project was the highly secret American atomic research study which led to the making of the atom bomb. What is not so well known is that before the Project, fluorine was a difficult and dangerous element, while afterwards it became a key ingredient in all the new inhalational anaesthetics.
openaire   +2 more sources

Low Latency Global Carbon Budget Reveals Late 2024 Carbon Losses and Contrasting Early 2025 Land Sink Recovery Signals

open access: yesAdvanced Science, EarlyView.
Low latency carbon budget estimates for July 2024–June 2025 combine atmospheric CO2 growth rates, fossil emissions, ocean uptake, DGVM land fluxes, and OCO‐2 inversions. The budget shows that late‐2024 land carbon losses dominate the annual anomaly, while early‐2025 recovery differs between bottom‐up models and top‐down inversions, especially in ...
Piyu Ke   +32 more
wiley   +1 more source

Third molar impaction

open access: yesOrapuh Journal, 2021
Third molar impaction is a pathological condition in which a ‘wisdom tooth’, which is the last permanent tooth to erupt in each quadrant of the oral cavity, lacks enough room to accommodate them and consequently fails to erupt or does not erupt properly.
VE ADAMU   +2 more
doaj  

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

open access: yesAdvanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge   +13 more
wiley   +1 more source

Kansas Natural Resources Legacy Alliance Final Report, 2003.

open access: yes, 2003
Cover title.; "December 1, 2003."; "As provided by the 2002 Kansas Legislature in SB 504, the Alliance was charged to 'develop a vision for using the state's natural resources to assure economic development, a healthy environment, proper protection of ...
Kansas Natural Resources Legacy Alliance.
core   +1 more source

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