Results 121 to 130 of about 9,016,584 (304)

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

open access: yesAdvanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng   +19 more
wiley   +1 more source

The practice of analytical psychotherapy, counselling and examination. Institute for legal psychology, Uster (Zurich), Switzerland [PDF]

open access: yesСовременная зарубежная психология, 2015
Psychotherapy is often regarded as a technique by which convicts can be changed in accordance with the wishes of society. Independent client activity is paid too little attention to. However, it is the one on which it depends whether the therapeutic work
Reinfried H.-W.
doaj  

Theoretical and Legal Foundations of the Automation of Legal Activities

open access: yesLegal Concept
Introduction: legal activities in the digital society are changing qualitatively. The methods of legal regulation are expanding, new forms and methods of implementation are emerging, and the material and technical base is being modernized. Automation is becoming a new direction for improving legal activities and, at the same time, a source of large ...
openaire   +1 more source

Feasibility of Group Legal Services in Australia: the Public's Attitude to Group Legal Services, 1980

open access: yes, 2019
One of several surveys conducted for the 'Feasibility of Group Legal Services in Australia' project, this survey examines the level of interest by the general public in the idea of group legal services schemes.
Evans, John, Jones, Roger
core   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

open access: yesAdvanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi   +12 more
wiley   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

open access: yesAdvanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong   +10 more
wiley   +1 more source

The evolving legal framework for private sector activity in Slovenia [PDF]

open access: yes
The government of Slovenia is moving rapidly to promote the growth of an efficient market economy and the private sector. One of the major tasks it faces is the development of a legal framework that can act as a decentralized"invisible hand"to replace ...
Gray, Cheryl W., Stiblar, Franjo D.
core  

Spatial and Temporal Dimensions for Legal History

open access: yes, 2016
"The spatiotemporal conjunction is a fundamental aspect of the juridical reflection on the historicity of law. Despite the fact that it seems to represent an issue directly connected with the question of where legal history is heading today, it still has

core   +1 more source

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

open access: yesAdvanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun   +12 more
wiley   +1 more source

Erratum to: On the issue of defining the essence of the object of the intangible cultural heritage: historical retrospective and significance for the development of modern society

open access: yesSHS Web of Conferences, 2018
Doguzhaeva Muminat   +4 more
doaj   +1 more source

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