Results 111 to 120 of about 141,687 (304)
Case study of the Below the Belt 'phone app: learning from projects that don’t meet expectations
, 2016 In early 2013 the Community Legal Education Program (CLE) at Victoria Legal Aid (VLA) planned a project to develop an interactive mobile phone application, offering targeted, relevant and free legal information to young people on legal issues that ...
Victoria Legal Aid
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G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source
Legal Aid Queensland contract disclosure report
Summary of current contracts valued over $10,000 for services provided to Legal Aid Queensland.Summary of Legal Aid Queensland awarded contracts - Summary of current contracts valued over $10,000 for services provided to Legal Aid Queensland.\r\n<br ...
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Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
Advanced Science, EarlyView.In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Legal service for defendants in Apprehended Domestic Violence Order (ADVO) proceedings: an evaluation [PDF]
, 2014 Aims: To determine: 1) whether providing legal advice to defendants in Apprehended Domestic Violence Order (ADVO) proceedings reduces the frequency with which ADVOs are breached; 2) what defendants and stakeholders think about the pilot legal advice ...
Lily Trimboli
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Advanced Science, EarlyView.We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua +6 more
wiley +1 more source
Legal Aid Queensland services by gender 2015-16
Services provided by Legal Aid Queensland by gender (male/female)Legal Aid Queensland services by gender 2015-16 - Services provided by Legal Aid Queensland by gender in the 2015-16 financial year.<br/>Legal Aid Queensland services by gender ...
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