Results 91 to 100 of about 5,603,296 (294)

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

open access: yesAdvanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun   +12 more
wiley   +1 more source

Victims of Violence: The Forced Sterilisation of Women and Girls with Disabilities in Australia

open access: yesLaws, 2017
This paper considers the issue of forced sterilisation of women and girls with disabilities in the Australian context. It examines the history and ideological underpinning of this practice, the current Australian regime and the present rationales for ...
Laura Elliott
doaj   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

A therapeutic approach to assessing legal capacity in Australia

open access: yes, 2015
Australia lacks a satisfactory, national paradigm for assessing legal capacity in the context of testamentary, enduring power of attorney and advance care directive documents.
Madison, Jeanne   +2 more
core   +1 more source

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li   +10 more
wiley   +1 more source

Pulford Justin, Crossman Susie, Begg Sara, Amegee Quach Jessica, Abomo Pierre, El Hajj Taghreed and Bates Imelda, 2020, "Strengthening research management and support services in sub-Saharan African universities and research institutions - anonymous data extraction"

open access: yes
Intermediary data extracted from 28 research management system capacity assessment reports completed in 25 universities/research institutions from across 15 sub Saharan-African countries between 2014 and ...
Centre for Capacity Research
core   +1 more source

Supramolecular Terbium‐Threonine Chiral Emitters with Tunable Circularly Polarized Luminescence as Anticounterfeiting‐Ink for Autonomous Data Encryption

open access: yesAdvanced Science, EarlyView.
A one‐pot, aqueous, and scalable method for synthesizing chiral lanthanide supramolecular emitters using terbium and threonine is reported. The aqueous solution of these chiral emitters displays the following features: (i) 100 % transparency, (ii) tunable luminescence and CPL, and (iii) a pH feedback loop that controls the “on‐off” states of ...
P. M. Ajay Sekhar   +5 more
wiley   +1 more source

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