Results 71 to 80 of about 1,810,158 (362)
Advanced Science, EarlyView.Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao +11 more
wiley +1 more source
Human Factors in Information-Age Trade Secret Protection [PDF]
, 2011 [Excerpt] Trade secret information security involves a multi-dimensional array of human, legal, and technological factors. I argue that organizational culture, employee policies, and other human factors are fundamental prerequisites to the successful ...
Elbaum, Dan
core +1 more source
Advanced Science, EarlyView.The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li +10 more
wiley +1 more source
Comparative legal studies and legal culture typology
RUDN Journal of Law, 2013 The author examines the methodological problems of comparative legal studies, focusing on the possibilities of the use socio-cultural approach and legal culture typology.
M V Nemytina
doaj
LEGAL CULTURE: YESTERDAY AND TODAY
Современная наука и инновации, 2022 The article describes the concept of legal culture and legal awareness, provide an analysis of historical and contemporary views, describing measures that would solve certain problems.
Maria I. Kruglikova
doaj
Human Trafficking and Legal Culture [PDF]
Israel Law Review, 2010 This Article discusses the Palermo Protocol to Prevent, Suppress and Punish Trafficking in Persons. In the first part it offers a critical discussion of what is entailed by speaking of a “shortfall” of enforcement in dealing with the social problem of human trafficking. It then goes on to show that there are two competing narratives of this problem and
openaire +3 more sources
Legal Culture Blindness and Canadian Indian Law [PDF]
, 1989 This paper explores the special problems that specialists in federal Indian law in the United States face when they attempt to understand the legal position of indigenous peoples in Canada, make comparisons and offer assistance and advice.
Conn, Stephen
core
Advanced Science, EarlyView.PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
ISSUES OF LEGAL CULTURE, LEGAL CONSCIOUSNESS AND LEGAL MENTALITY IN KAZAKHSTANI SOCIETY
Хабаршы. Заң сериясыEffective functioning of all elements is important for the legal system. The legal system is a system capable of changing its own structure in the course of activity.
D. Bakirov +4 more
doaj +1 more source