Results 41 to 50 of about 60,292 (299)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
The legal discourse on the case Romina Tejerina: a look at key gender
Punto Género, 2013 It is the aim of this article to replace and problematize on some legal discourses about the case of Romina Tejerina, providing special attention to the gendered dimension on them.
María Laura Martinetti
doaj +1 more source
Critical Social Work, 2023 In this article, we examine the representations of Finnish children living in the al-Hol refugee camp in Eastern Syria. Our data consists of materials published in 2019 in the Helsingin Sanomat, the largest subscription-based newspaper in Finland ...
Laura Lagus +2 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2022 International Journal of Recent Research in Social Sciences and Humanities (IJRRSSH), ISSN 2349-7831, Paper Publications, Website: www.paperpublications ...
Cyril A. Etim, Emmanuel E. Ette
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Suggestive Mechanisms in Legal Discourse
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2017 This article is devoted to investigating the mechanisms of suggestive influence in plaintiff and defendant's opening statements. The terms "persuasion", "manipulation (suggestion)", "suggestive strategy" and "suggestive tactics" are analysed.
Veronika V. Katermina +1 more
doaj +1 more source
Comparative methods in the Italian legal discourse on labour: notes on the origins,
, 2023 The paper aims to discuss convergences and encounters of legal cultures from the viewpoint of the ‘comparative methods’ employed in nineteenth- and twentieth-century Italian legal discourse on ...
Carolina Argiroffi
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source