Results 111 to 120 of about 6,461,136 (249)
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen +13 more
wiley +1 more source
Pseudolaw and the illusion of legal meaning [PDF]
This article is an overview of the contemporary phenomenon of pseudolaw and argues that, at its heart, it involves a mistaking of the form of legal argumentation for its substance. Essentially, through the use of legalistic language, archaic sources and strange rituals, an illusion of legal meaning is created which tricks users into believing their ...
openaire +1 more source
Title from cover (i.e. p. [1]) of PDF document (viewed July 28, 2006).; "This publication was produced by Ohio Legal Rights Service through a contract with National Alliance on Mental Illness (NAMI) Ohio and with funding from the Ohio Department of ...
Ohio Legal Rights Service.
core
Boulder Statement on Legal Research Education [PDF]
The Conference on Legal Information: Scholarship and Teaching was attended by legal research professionals who gathered at the University of Colorado Law School in Boulder, Colorado on June 21-22, 2009, to discuss legal information scholarship and ...
Legal Information Conference Attendees
core
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Providing digital security of healthcare system with criminal-legal means
Objective: to develop a comprehensive system of ethical principles for the formation of a regulatory framework and the practical implementation of digital bioprinting technologies in clinical practice.Methods: the research is based on the application of ...
A. A. Shutova, I. R. Begishev
doaj +3 more sources
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang +27 more
wiley +1 more source
The Legal Limits of “Yes Means Yes” [PDF]
This op-ed piece for the Chronicle of Higher Education argues that the affirmative consent rule of yes means yes is a useful standard that can help educate and ideally change norms regarding consent to sexual intercourse.
Robinson, Paul H.
core
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu +8 more
wiley +1 more source
The fabrication of wide‐bandgap perovskite thin films via green solvents integrated with inkjet printing is developed. Controlled crystallization of the perovskite layer is achieved by optimizing ink formulation and additive engineering, enabling power conversion efficiencies above 17% for single junctions and 28% for perovskite/silicon tandem solar ...
Uma Kousalya Dangudubiyyam +12 more
wiley +1 more source

