Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression
Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar +6 more
wiley +1 more source
Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome
Objectives VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani +10 more
wiley +1 more source
Personality Disorder Diagnoses in Outpatient Forensic Mental Health: A Comprehensive Prevalence Study in the Netherlands. [PDF]
Van Reijswoud BE +5 more
europepmc +1 more source
Body donor programs in Australia and New Zealand: Current status and future opportunities
Abstract Body donation is critical to anatomy study in Australia and New Zealand. Annually, more than 10,000 students, anatomists, researchers, and clinicians access tissue donated by local consented donors through university‐based body donation programs. However, little research has been published about their operations.
Rebekah A. Jenkin, Kevin A. Keay
wiley +1 more source
Contextual Anthropocentrism and Animal Welfare Attitudes Among German Livestock Farmers: Evidence from Survey Data. [PDF]
Mergenthaler M, Schröter I.
europepmc +1 more source
Histories in bone: Navigating the ethical landscape of human skeletal collections in South Africa
Abstract Provenance is at the center of addressing the complicated ethical stewardship of legacy human skeletal collections. Many South African (SA) health science institutions have skeletal collections. While the history of the collections and the demographics of the skeletons have been reported, the provenance of the individuals within the ...
Quenth Chinenere +2 more
wiley +1 more source
Pseudologia Fantastica: A Systematic Review of Sociodemographic Features and Psychiatric Comorbidities [PDF]
Sharma V +6 more
europepmc +2 more sources
Identifying suicide risk in veterans with criminal-legal system involvement: A latent profile analysis of criminogenic needs and posttraumatic stress symptoms. [PDF]
Fortuna AJ +5 more
europepmc +1 more source
Abstract The study of human anatomy is foundational to education and research in the anatomical and health sciences. In 2012, the International Federation of Associations of Anatomists (IFAA) first published Recommendations to promote ethical practice in the acquisition of human remains for this purpose.
D. Gareth Jones +9 more
wiley +1 more source

