Results 171 to 180 of about 212,559 (264)

Shadow Infrastructures of Labour: A Case Study of Generative AI Use in Victorian Child Protection Practice

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Generative Artificial Intelligence (GenAI) tools such as ChatGPT are rapidly entering workplaces, yet their use in frontline human services remains largely undocumented and weakly regulated. Drawing on an investigation into a child protection worker's informal use of ChatGPT, this article provides insight into how GenAI is already shaping ...
Joel Robert McGregor   +3 more
wiley   +1 more source

Construction and evaluation of a chronic arthritis animal model induced by persistent activation of toll‐like receptors via lipopolysaccharide stimulation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We constructed a novel systemic juvenile idiopathic arthritis mouse model (LC) by introducing sustained TLR4 activation into the collagen‐induced arthritis model. The LC model effectively recapitulates human sJIA‐like systemic inflammation while revealing a critical dissociation between systemic immune activation and joint damage.
Fengming Li   +4 more
wiley   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

open access: yesThe Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson   +6 more
wiley   +1 more source

Body mass and sex estimation from lower carnassial tooth morphometry in the endangered Iberian wolf (Canis lupus signatus): An ecomorphological analysis of sexual size dimorphism

open access: yesThe Anatomical Record, EarlyView.
Abstract The Iberian wolf (Canis lupus signatus) is an endangered subspecies characterized by highly fragmented populations and increasing human–carnivore conflict across the Iberian Peninsula. Although body mass strongly influences predator–prey dynamics and ecological performance, quantitative assessments of sexual size dimorphism (SSD) and body mass
Leonardo Cotts   +4 more
wiley   +1 more source

Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani   +10 more
wiley   +1 more source

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