Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang +5 more
wiley +1 more source
Legal and ethical conflicts in hospital settings: thematic synthesis of qualitative studies focused on nursing practice. [PDF]
Yarahmadi S, Cheraghian T, Jafarifar S.
europepmc +1 more source
Legal Protection for Person with Disabilities in Relating Right to Vote on the Indonesian Election
Dewi Nurvianti, Zulvia Makka
openalex +2 more sources
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Between fiscal returns and social harm: reframing gambling regulation in Kazakhstan through international evidence. [PDF]
Khamzina Z, Buribayev Y.
europepmc +1 more source
Constitutional Protection for Group Legal Service Plans
Robert R. Rossi
openalex +1 more source
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Fetal rights from Islamic and contemporary legal perspectives: a scoping review. [PDF]
Kakrodi SP +3 more
europepmc +1 more source
Implementation of Legal Protection for Women Victims of Physical Violence by Police Investigators of the Women and Child Protection Unit [PDF]
Mustika Payung +2 more
openalex +1 more source
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti +9 more
wiley +1 more source

