Results 91 to 100 of about 7,724 (303)
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin +11 more
wiley +1 more source
Does the use theory of meaning entail legal realism?
It is argued that there is a close connection between Wittgenstein’s UseTheory of Meaning (UT) and Legal Realism (LR). Therefore, if you accept one, you can hardly avoid accepting the other, on pain of inconsistency.
Seppo Sajama
doaj +1 more source
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi +12 more
wiley +1 more source
Jurisprudential Responses to Legal Realism
The intellectual movement we call legal realism is today, I think, most often thought of as having an exclusively negative or critical character. But while this movement historically has had a strongly negative component, it has also had a positive or ...
Kronman, Anthony Townsend +1 more
core +1 more source
Concept of Russian Legal Realism in the Postclassical Paradigm
Introduction. Postclassical jurisprudence is characterized by the integration of an analytical and empirical approach to researches, which has been notably evident in recent decades.
E. N. Tonkov
doaj
Book Review: Legal Realism at Yale, 1927-1960
Laura Kalman\u27s monograph, originally a dissertation, is nevertheless a fresh and rather engaging study of a finished chapter in intellectual history—the legal realist movement.
Brown, Ralph S., Jr.
core
Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang +6 more
wiley +1 more source
À l’occasion de la parution de son dernier ouvrage (Whitman, 2017), il a paru utile de revenir sur les travaux de James Q. Whitman, professeur d’histoire du droit et de droit comparé à l’Université de Yale.
James Q. Whitman +2 more
doaj +1 more source
How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang +4 more
wiley +1 more source
This Article begins to rethink current conceptions of two of the most significant legal movements in this country1—Legal Realism and Feminist Jurisprudence. The story of Legal Realism has been retold for decades.
Quinn, Mae C.
core +1 more source

