Results 41 to 50 of about 7,724 (303)

Law and Rationality: A Historiographical Investigation of the Understanding of Motivation and Human Agency in Early Legal Anthropology

open access: yesClio@Themis, 2019
The purpose of this article is to examine how nineteenth-century legal science conceptualized and dealt with otherness in law, with examples of legal phenomena such as ordeal and blood revenge to illustrate how the concept of legal rationality evolved in
Kaius Tuori
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Roscoe Pound e la concezione teleologica del diritto: tra giuridicità e metagiuridicità [PDF]

open access: yesDemocrazia e Diritti Sociali, 2023
This paper intends to delve into Roscoe Pound’s thought, enhancing his teleological conception of law as a key to understanding Pound’s historicism, pragmatism and functionalism. The Author will also deal with the Poundian contribution within a ‘situated’
Rosaria Pirosa
doaj  

Possibility and impossibility of interdisciplinary studies in LAW Case study: sociology of public law [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2020
Interdisciplinary studies are currently a hot topic in legal academia, therefore one should distinguish four types in the sociological approach to law: disciplinary, interdisciplinary, multidisciplinary and transdisciplinary studies.
Mahdi Mahdavizahed
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Predictive analysis of judicial behavior: Return to mechanical jurisprudence? [PDF]

open access: yesCrimen (Beograd), 2018
This paper is about the roots of computerized predictive analysis of judge's behavior, and it investigates problems which predictive analysis is facing today, its prospects, as well as advantages and limits of that method.
Avramović Dragutin
doaj  

Mandatory and Default Rules in Private Law

open access: yesBratislava Law Review, 2020
The paper summarizes philosophical, historical and doctrinal background of the differentiation between mandatory and default rules in private law in general and in company law in particular. The conclusion of the author is the plea to provide for a clear
Tomáš Gábriš
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

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