Results 81 to 90 of about 1,414,184 (301)

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

open access: yesAdvanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

On Fragments and Geometry: The International Legal Order as Metaphor and How it Matters [PDF]

open access: yes, 2013
This article engages the narrative of fragmentation in international law by asserting that legal academics and professionals have failed to probe more deeply into ‘fragmentation’ as a concept and, more specifically, as a spatial metaphor.
Rajkovic, Nikolas M.
core   +1 more source

Pergulatan Hukum Positivistik Menuju Paradigma Hukum Progresif [PDF]

open access: yes, 2010
The legal reform is not only reform the legal substance but also to reform the legal structure and the legal culture including legal ethic and legal science.
Swardhana, G. M. (Gde)
core   +2 more sources

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao   +11 more
wiley   +1 more source

La représentation de la nature devant le juge : Plaidoyer pour une épistémologie juridique du fictif

open access: yesVertigO, 2015
This paper explores the concept of Nature in a historical and theoretical dimension. The concept has two essential meanings for the legal scholar. Narrowly defined, that is in an ecological sense, it is known as the subject matter of a specialized branch
Jochen Sohnle
doaj   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

open access: yesAdvanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li   +10 more
wiley   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

open access: yesAdvanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li   +8 more
wiley   +1 more source

The Performative Nature of Legal Language and the Construction of Legal Reality

open access: yesТеоретическая и прикладная юриспруденция
Introduction. The article examines the normativity of legal language through the lens of speech act theory, emphasizing its performative nature. The author argues that legal language cannot be reduced to a purely descriptive function: it not only refers ...
V. V. Ogleznev
doaj  

Certainty and truth in Law

open access: yesEstudios de Deusto, 2014
This article analyzes the relationship between natural truth and legal truth. What the law says and affirms as true, according to his authority, does not always correspond with the truth, perceived or discovered by reason.
Agustín Luna Serrano
doaj   +1 more source

Home - About - Disclaimer - Privacy