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Legal Reasoning: Logic, Interpretation and Argumentation

open access: yesRevista Facultad de Jurisprudencia, 2018
The present work will investigate in the most important aspects of the logic of the reasonable, in which the argument plays a fundamental role and while the juridical interpretation, is not alien. Legal reasoning seeks as the ultimate goal the search for
Mabell Abigail Lagla Pillajo
doaj   +1 more source

Can One Really Reason about Laws? [PDF]

open access: yes, 1999
Precedent decides legal cases, but few precedents make the case at bar res judicata. Instead, analogical reasoning is used, together with canons of statutory interpretation and theories of constitutional jurisprudence. The work under review provides a
Fulda, Joseph S.
core  

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li   +22 more
wiley   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao   +11 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

Discovering Interpretable Semantics from Radio Signals for Contactless Cardiac Monitoring

open access: yesAdvanced Science, EarlyView.
This study presents a semantic representation framework for clinically interpretable cardiac monitoring from contactless radio signals. It formulates radio semantic learning as an information‐bottleneck problem and approximates the objective via intra‐modal compression and cross‐modal alignment, structuring radio measurements into meaningful semantic ...
Jinbo Chen   +10 more
wiley   +1 more source

Of Artificial Intelligence and Legal Reasoning [PDF]

open access: yes, 2014
Can computers, or artificial intelligence, reason by analogy? This essay urges that they cannot, because they are unable to engage in the crucial task of identifying the normative principle that links or separates cases. Current claims, about the ability
Sunstein, Cass Robert
core  

Competition Policy and Agribusiness in the Biden Administration

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT The Biden Administration pursued a set of ambitious competition policy initiatives in agriculture and agribusiness, primarily aimed at livestock and poultry supply chains, farm inputs, and food retailing. The initiatives included expanded antitrust enforcement; new US Department of Agriculture (USDA) contract regulations requiring poultry ...
James M. MacDonald
wiley   +1 more source

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