Results 41 to 50 of about 1,713,760 (308)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Social and legal regulators. Conceptual developments by V.I. Nizhechek

RUDN Journal of Law
The role of the Soviet scientist-activist V.I. Nizhechek in the development and establishment of social regulation concepts, and its importance in governing societal affairs, as well as functions and potential of law, and its relationship with morality ...
Nikolai A. Vlasenko
doaj   +1 more source

Principles of Introducing the Institution of Mediation in Public Legal Disputes in Ukraine

Bulletin of Kharkiv National University of Internal Affairs, 2020
The article is focused on theoretical study of the principles of introduction of the institution of mediation in public law disputes in Ukraine. It has been determined that the introduction of mediation in the field of public administration should be ...
K. S. Tokarieva
doaj   +1 more source

Reforming the public sector in the EU: the new public procurement regime [PDF]

, 2005
Commentary on the significance of the regulation of public procurement in the common market and impact on increased potential for doing business with the public sector.
Bovis, Christopher
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Biomedical Research Involving Prisoners: Ethical Values and Legal Regulation [PDF]

, 2007
Until the early 1970\u27s, approximately 90% of all pharmaceutical research was conducted on prisoners, who were also subjected to biochemical research, including studies involving dioxin and chemical warfare agents.
Gostin, Lawrence O.
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Modernization of the Legal System of Ukraine: Sociocultural Dimension

Науково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького
Purpose. The purpose of the research is the theoretical characterization of some external system connections that determine the functional state of the legal system of Ukraine and are able to play a decisive role in the process of its modernization ...
Hladkyi S.
doaj   +1 more source

Autonomous regulation: Legal theory qualification and positive law frameworks [PDF]

Pravni Zapisi, 2018
The issue of the autonomous regulation in this academic work was intepreted through historical, theoretical and comparative standpoints of legal manner. Following the introductory remarks on the process of strengthening the executive power in the new-era
Stevandić Danilo
doaj