Results 111 to 120 of about 4,224,198 (351)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

ON CHALLENGING POINTS OF THE FORMULATION OF RESPONSIBILITY IN THE SOVIET CIVIL LAW

open access: yesГуманитарные и юридические исследования, 2021
Questions of guilt of the individual, the reasons causing his guilty behavior and also negative consequences of these processes are a subject of consideration not only within the framework of psychological and philosophical science, but in law as well ...
H. V. Idrisov
doaj  

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

open access: yesAdvanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger   +17 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Responsibility for administrative delicts within banking operations

open access: yesLaw and Safety, 2018
The article is focused on scientific problems of administrative law. The author analyzed the scientific notions of administrative responsibility. The author gave a definition of administrative responsibility for administrative delicts within banking ...
M. Yu. Bukreev
doaj   +1 more source

LEGALITY AS THE PRINCIPLE OF LEGAL RESPONSIBILITY

open access: yesScientific Herald of Sivershchyna. Series: Law, 2023
The article is devoted to the characteristics of the principle of legality in the context of its application as a principle of legal responsibility, which is inherent in all branches of law, including financial law and tax law, as a sub-branch of the latter.
openaire   +1 more source

Morse, Mind, and Mental Causation [PDF]

open access: yes, 2014
Stephen Morse’s illuminating scholarship on law and neuroscience relies on a “folk psychological” account of human behavior in order to defend the law’s foundations for ascribing legal responsibility. The heart of Morse’s account is the notion of “mental
Pardo, Michael S., Patterson, Dennis
core   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

open access: yesAdvanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen   +8 more
wiley   +1 more source

ADMINISTRATIVE RESPONSIBILITY (THE CONSTITUTIONAL DESIGN)

open access: yesГуманитарные и юридические исследования, 2021
The article studies basic elements of the constitutional design of the administrative responsibility: proportionality of the restriction of citizens' rights and freedoms to the constitutionally signiicant interests and goals; presence of guilt as an ...
I. V. Maximov
doaj  

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