Results 111 to 120 of about 6,894,902 (255)

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

open access: yesAdvanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun   +12 more
wiley   +1 more source

Immigrant Legal Resource Center

open access: yes, 2019
The Immigrant Legal Resource Center (ILRC) was founded in 1979 by law professor Bill Ong Hing to help immigration law professionals and advocates develop their expertise, educate immigrant communities to advocate for themselves, and shape immigration ...
Immigrant Legal Resource Center
core  

Multisensory legal machines and legal act production [PDF]

open access: yes, 2012
This paper expands on the concept of legal machine which was presented first at IRIS 2011 in Salzburg. The research subjects are (1) the creation of institutional facts by machines, and (2) multimodal communication of legal content to humans.
Lachmayer, Friedrich, Čyras, Vytautas
core  

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Legal status of immigrants and criminal behavior: evidence from a natural experiment [PDF]

open access: yes
We estimate the causal effect of immigrants' legal status on criminal behavior exploiting exogenous variation in migration restrictions across nationalities driven by the last round of the European Union enlargement.
Paolo Pinotti, Giovanni Mastrobuoni
core  

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li   +10 more
wiley   +1 more source

From "mud houses" to "wasted houses": remittances and housing in rural highland Ecuador

open access: yesREMHU: Revista Interdisciplinar da Mobilidade Humana, 2014
Migration is often aimed to build migrants' own house in their places of origin. In rural highland Ecuador remittances sent from the US are habitually used to build houses which have changed the housing landscape of many villages.
Diana Mata Codesal
doaj  

Supramolecular Terbium‐Threonine Chiral Emitters with Tunable Circularly Polarized Luminescence as Anticounterfeiting‐Ink for Autonomous Data Encryption

open access: yesAdvanced Science, EarlyView.
A one‐pot, aqueous, and scalable method for synthesizing chiral lanthanide supramolecular emitters using terbium and threonine is reported. The aqueous solution of these chiral emitters displays the following features: (i) 100 % transparency, (ii) tunable luminescence and CPL, and (iii) a pH feedback loop that controls the “on‐off” states of ...
P. M. Ajay Sekhar   +5 more
wiley   +1 more source

The Impact of Irregular Status on Human Development Outcomes for Migrants [PDF]

open access: yes
The purpose of this paper is to explore how irregular status impacts a range of human development outcomes for labour migrants. The analysis indicates that for poorer labour migrants, irregular (or undocumented) migration provides a positive, private ...
Rachel Sabates-Wheeler
core   +2 more sources

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