Results 111 to 120 of about 720,019 (308)

Legal status and manifestation of power: The Roman customs post Turicum (Zürich)

open access: yes, 2019
The Roman Small Town Turicum/Zürich is an epigraphically attested customs station of the Gallic customs district (quadragesima galliarum) – a legal status that is very rarely found for Roman settlements.
Wyss, Annina
core  

The development of the Chinese legal profession since 1978 [PDF]

open access: yes, 1998
This thesis focuses on introducing the development of, and changes in, the Chinese legal profession over this past twenty years, analysing the reasons that led to these changes, and considering both theoretical and practical problems.
Hu, Juan
core  

DRIVE‐SAFE: Data‐Driven Robustness and Informed Validation for Evolving Specifications via Formal Evaluation

open access: yesAdvanced Robotics Research, EarlyView.
DRIVE‐SAFE evaluates learning‐based, black‐box autonomous driving policies against evolving temporal safety requirements using Signal Temporal Logic robustness metrics. It aggregates distributional robustness measures with domain‐informed weights to guide iterative retraining.
Kristy Sakano   +3 more
wiley   +1 more source

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

open access: yesAdvanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu   +9 more
wiley   +1 more source

PHARMACOLOGY OF CANNABINOIDS

open access: yesZdravniški Vestnik, 2015
The discovery of cannabinoid receptors and endocannabinoid system has led to the potential therapeutic use of cannabis derivatives. Cannabinoids acting through the CB1 receptors modulate the release of other neurotransmitters in central nervous system ...
Ilonka Ferjan   +5 more
doaj  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

СТАРАТЕЛИ В СОВЕТСКОЙ ЗОЛОТОДОБЫВАЮЩЕЙ ПРОМЫШЛЕННОСТИ: СТАНОВЛЕНИЕ СОЦИАЛЬНО-ПРАВОВОГО СТАТУСА

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2013
В статье отражены основные направления нормативно-правового регулирования деятельности старательских артелей в золотодобывающей промышленности СССР. Особое внимание уделено взаимосвязи между постоянной потребностью государства в золоте, обеспечением ...
Елена Даниловна Кочегарова
doaj  

Did Employer Sanctions Lose Their Bite? Labor Market Effects of Immigrant Legalization [PDF]

open access: yes
Taking advantage of the ability to identify immigrants who were unauthorized to work prior to obtaining Legal Permanent Resident status, we use the New Immigrant Survey to examine whether lacking legal status to work in the U.S.
Hill, Laura E.   +2 more
core  

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

open access: yesAdvanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu   +19 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

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