Results 101 to 110 of about 174,242,376 (300)

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Patent applications in Brazil on veterinary antiparasitics [PDF]

Anais da Academia Brasileira de Ciências
Brazil is an important cattle producer and the world’s third-largest pet market, with the second-highest number of dogs. This makes antiparasitic drugs crucial in the animal health sector, addressing a wide range of parasites affecting livestock and pets.
CECILIA CAROLINE S. ALVES, MARIA DA GLÓRIA A. BANDEIRA, ALEXANDRA M.S. SOARES   +2 more
doaj   +1 more source

[Human being and animals: different ontological and legal status].

Cuadernos de bioetica : revista oficial de la Asociacion Espanola de Bioetica y Etica Medica, 2021
The different legal status of human being and animals is a consequence of their different ontological status. Human being has dignity, which requires the recognition of rights that ensure a dignified life. The animal lacks dignity, but it must be protected by law, even though it does not have recognized rights.
openaire   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

Advanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang   +13 more
wiley   +1 more source

Feline events beyond pet ownership paradigm: An ethnographic case report on end-of-life decision-making for NONAME 6796

Human-Animal Interactions
Background: The human–animal bond is most often understood within the framework of the “pet ownership paradigm,” which defines a permanent relationship between an animal and their legal guardian.
Burak Taşdizen
doaj   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

THE SUI GENERIS LEGAL STATUS OF ANIMAL IN THE CORPUS IURIS CIVILIS

, 2019
It is studied the animal’s legal status in the Corpus Iuris Ciulis Institutiones. Therefore, it is questioned the traditional and reductionist way of thinking that identifies those being simply as things, evidencing clues to sui generis character, through a rereading of the Institutes.
HERON JOSÉ DE SANTANA GORDILHO, CRISTÓVÃO JOSÉ DOS SANTOS JÚNIOR   +1 more
openaire   +1 more source

Animal Custody Disputes: A Growing Crack in the Legal Thinghood of Nonhuman Animals

, 2000
Despite the traditional view of animals as mere chattels, courts are increasingly viewing animals as more than things, recognizing the intrinsic value of animal companions. With the help of organizations such as the Animal Legal Defense Fund, case law,
Newell, Barbara
core  

Legal Status Of Land Rights, Reclamation Results [PDF]

, 2019
The purpose of this study is to find out the legal status of land rights resulting from coastal and marine reclamation, regulations regarding coastal reclamation have not been clearly regulated in Indonesia, so that it is often very detrimental to the ...
Kusumawati, Lanny
core  

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source