Results 121 to 130 of about 20,447,157 (300)

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li   +10 more
wiley   +1 more source

Structure of National Security Legislation: Theoretical Foundations and Systematisation Issues

open access: yesLaw and Safety
The article discusses the problems of fragmentation and insufficient internal consistency of Ukraine’s national security legislation. It is noted that these issues have become particularly acute in the context of martial law, and there is an urgent need ...
Yu. O. Zahumenna, K. A. Voloshyn
doaj   +1 more source

Supramolecular Terbium‐Threonine Chiral Emitters with Tunable Circularly Polarized Luminescence as Anticounterfeiting‐Ink for Autonomous Data Encryption

open access: yesAdvanced Science, EarlyView.
A one‐pot, aqueous, and scalable method for synthesizing chiral lanthanide supramolecular emitters using terbium and threonine is reported. The aqueous solution of these chiral emitters displays the following features: (i) 100 % transparency, (ii) tunable luminescence and CPL, and (iii) a pH feedback loop that controls the “on‐off” states of ...
P. M. Ajay Sekhar   +5 more
wiley   +1 more source

Sign language interpreters and auxiliary aids and services a publication of the Ohio Legal Rights Service (OLRS).

open access: yes, 2003
Graphical and text-only/printer-friendly versions provided.; Description based on: Nov. 2003 version; title from Home page caption (viewed on Dec. 13, 2007).; Harvested from the web on 12/13/07Introduction -- Provision of sign language interpreters ...
Ohio Legal Rights Service.
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Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

open access: yesAdvanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang   +14 more
wiley   +1 more source

Immigrant Legal Resource Center

open access: yes, 2019
The Immigrant Legal Resource Center (ILRC) was founded in 1979 by law professor Bill Ong Hing to help immigration law professionals and advocates develop their expertise, educate immigrant communities to advocate for themselves, and shape immigration ...
Immigrant Legal Resource Center
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A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

open access: yesAdvanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan   +11 more
wiley   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

open access: yesAdvanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan   +13 more
wiley   +1 more source

News; News from OLRS

open access: yes, 2008
Aug. 2008; Vol. 1, issue 1 (Nov. 2008)-; "Ohio's Protection & Advocacy System for People with Disabilities."; Description based on: Aug. 2008; title from PDF caption (viewed May 4, 2009).; Newsletter; information and updates about OLRS' case work and ...
Ohio Legal Rights Service.
core  

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