Results 41 to 50 of about 3,970,671 (303)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Проблеми Законності, 2017 modern Ukraine on the way of reforming the legal system in accordance with European standards. It is concluded that at the present stage of state building the unitary form of the state structure is optimal.
Ольга Олександрівна Сидоренко
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Administrative Regulations: Concept, Features, Problems of a Legal Regulation
Теоретическая и прикладная юриспруденцияThe article analyzes a variety of normative legal acts, which is relatively new for the Russian legal system — administrative regulations. Signs that distinguish administrative regulations from other departmental regulatory legal acts are identified. The
V. A. Lushnikova
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Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
The legal system as a social phenomenon: concept, conten, structure
Теорія і практика правознавства, 2016 This article makes stress that the theoretical development of the concept of modern legal system represents one of the main tasks, the solution of which in fluences the nature of many legal problems connected with the improvement of present legislation ...
М. Б. Хаустова
doaj +1 more source
Prison-based Education and Its New Pedagogical Perspective [PDF]
, 2014 This article presents how unconventional teaching environments, such as the prison system, can participate in the elaboration of new pedagogical methods and, in the process, reveal the diverse responses of marginalized groups to the study of the law ...
Germain, S.
core +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Permanent Legal Immigration to the United States: Policy Overview [PDF]
, 2014 Four major principles currently underlie U.S. policy on legal permanent immigration: the reunification of families, the admission of immigrants with needed skills, the protection of refugees, and the diversity of admissions by country of origin.
Kandel, William A
core +2 more sources