Results 111 to 120 of about 2,984,237 (306)

Understanding the pharmaceutical patent system in Spain and Europe: a perspective from the need to take its protection-access tradeoff seriously [PDF]

open access: yes, 2020
As a result of the doctoral research developed by the main author (Vargas-Chaves, 2017), it was identified the evolution and perspectives of the pharmaceutical patent in the international trade system, as well as it future legal research needs in this ...
López-Oliva, José   +1 more
core  

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

open access: yesAdvanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

IMMIGRATION POLICY AND THE AGRICULTURAL LABOR MARKET: THE EFFECT ON JOB DURATION [PDF]

open access: yes
We have proposed and estimated a Heckman-type two stage model with legal status of farm workers using an ordered probit model in the first stage and a duration model in the second stage. Using the National Agricultural Workers Survey, self-reported legal
Emerson, Robert D.   +2 more
core   +1 more source

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

open access: yesAdvanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu   +9 more
wiley   +1 more source

Is Subjectivity Possible - the Post-Modern Subject in Legal Theory [PDF]

open access: yes, 1991
This article puts forward a thesis and then attempts to prove (or at least to develop) that thesis in two related areas. The thesis is that legal theory in general, and critical legal theory in particular, has concentrated too much on critiques of ...
Boyle, James
core   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Právní vědomí – několik poznámek

open access: yesČasopis pro Právní Vědu a Praxi, 2016
The article deals with introduction of the term legal consciousness. Firstly some definitions of legal awareness are presented (using works of important legal theorists or sociologists – for example Viktor Knapp, Manfred Rehbinder and many more ...
Tereza Krupová
doaj  

Structured Dialogue on Building a Sustainable, Stable Immigration Enforcement System [PDF]

open access: yes, 2015
This conversation occurred on October 24, 2014, ten days before the mid-term elections that gave Republicans control of the U.S. Senate for the first time since 2007 and increased their majority in the House of Representatives.
Abrams, Kerry
core   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

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