Results 201 to 210 of about 3,180,602 (246)

Accelerating the Roll‐Out of Modular Plants: From Engineering and Approval to Operation of Energy‐Efficient Modular Plants

open access: yesChemie Ingenieur Technik, EarlyView.
In the ENPRO REUNION project, a manufacturer‐independent modular plant concept was demonstrated by commissioning a pilot plant that integrated modules from different vendors and by expanding the module pool to include extraction and crystallization units.
Laura Marsollek   +8 more
wiley   +1 more source

Toward Intelligent Carbon Management: A Systems‐Based Framework for Social and Technological Assessment in CCU Applications

open access: yesChemie Ingenieur Technik, EarlyView.
A systems‐based framework integrates nine dimensions of CCU assessment with multi‐criteria scoring, weighting, scenario analysis, and dynamic weighting to support context‐sensitive decision‐making. ABSTRACT Carbon capture and utilization (CCU) technologies are increasingly recognized as key instruments for reducing greenhouse gas emissions while ...
Afshin Poorkhanalikoudehi   +4 more
wiley   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit   +6 more
wiley   +1 more source

Special Populations in Pivotal Clinical Trials: Eligibility and Supporting Evidence for Exclusion in EMA‐Authorised Medicines

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Evidence on the efficacy and safety of medicines supporting marketing authorization is largely derived from randomized controlled trials, yet these trials often exclude populations likely to use the medications in clinical practice. This study assessed eligibility of special populations, defined as pregnant and breast‐feeding individuals, elderly ...
Maja J. Jørgensen   +2 more
wiley   +1 more source

Analysis of Suffix Use for Biosimilar Product Identification in Postmarketing Adverse Event Reporting

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurate identification of medicines used in adverse event reports is crucial for effective postmarketing safety surveillance. The US Food and Drug Administration's (FDA) four‐letter suffix naming convention was designed to facilitate accurate biological product identification, but the extent to which these suffixes have been incorporated into ...
Danijela Stojanovic   +3 more
wiley   +1 more source

“Efforts to Surface the Unspoken”: A Mixed Methods Study of a Risk‐Informed Check‐In in Norwegian Family Mediation

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT In family mediation, emotional discomfort and perceived unsafety may signal deeper relational risks, including postseparation violence. Standard intake procedures in Norwegian family mediation depend on disclosure to a nonclinical administrator before any therapeutic relationship exists, and research documents systematic under‐reporting at ...
Jan Stokkebekk   +2 more
wiley   +1 more source

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